| # | Nom | Équipe | Buts | Pén | |
|---|---|---|---|---|---|
| 1 |  | Edin Džeko | AS Rome | 29 | 1 |
| 2 |  | Dries Mertens | SSC Naples | 28 | 2 |
| 3 |  | Andrea Belotti | Torino FC | 26 | 2 |
| 4 |  | Gonzalo Higuaín | Juventus | 24 | 0 |
 | Mauro Icardi | Inter Milan | 24 | 3 | |
| 6 |  | Ciro Immobile | Lazio de Rome | 23 | 6 |
| 7 | | Lorenzo Insigne | SSC Naples | 18 | 2 |
| 8 | | Keita Baldé | Lazio de Rome | 16 | 2 |
 | Marco Borriello | Cagliari Calcio | 16 | 1 | |
 | Papu Gómez | Atalanta Bergame | 16 | 2 | |
| 11 |  | Nikola Kalinić | ACF Fiorentina | 15 | 1 |
| Mo Salah | AS Rome | 15 | 0 | |
| 13 | | José Callejón | SSC Naples | 14 | 0 |
| 14 |  | Carlos Bacca | AC Milan | 13 | 4 |
 | Diego Falcinelli | Sassuolo Calcio | 13 | 2 | |
| 16 | | Grégoire Defrel | Sassuolo Calcio | 12 | 1 |
| Marek Hamšík | SSC Naples | 12 | 0 | |
| Iago Falque | AS Rome | 12 | 2 | |
 | Fabio Quagliarella | Sampdoria | 12 | 3 | |
 | Giovanni Simeone | Genoa CFC | 12 | 1 | |
 | Cyril Théréau | Udinese Calcio | 12 | 1 | |
| 22 | | Federico Bernardeschi | ACF Fiorentina | 11 | 3 |
 | Mattia Destro | Bologna FC | 11 | 0 | |
| Paulo Dybala | Juventus | 11 | 3 | |
| Luis Muriel | Sampdoria | 11 | 4 | |
| Radja Nainggolan | AS Rome | 11 | 0 | |
 | Ilija Nestorovski | Palermo FC | 11 | 1 | |
| Ivan Perišić | Inter Milan | 11 | 0 | |
| Patrik Schick | Sampdoria | 11 | 0 | |
| 30 | | Khouma Babacar | ACF Fiorentina | 10 | 1 |
 | Roberto Inglese | Chievo Verona | 10 | 0 | |
| Adem Ljajić | AS Rome | 10 | 1 | |
| Duván Zapata | Udinese Calcio | 10 | 1 | |
| 34 |  | Gianluca Caprari | Delfino Pescara | 9 | 1 |
| Sergio Pellissier | Chievo Verona | 9 | 3 | |
| 36 | | Andrea Conti | Atalanta Bergame | 8 | 0 |
| Blerim Džemaili | Bologna FC | 8 | 0 | |
| Éder Citadin | Inter Milan | 8 | 0 | |
| Stephan El Shaarawy | AS Rome | 8 | 0 | |
| Gianluca Lapadula | AC Milan | 8 | 2 | |
| Alessandro Matri | Sassuolo Calcio | 8 | 0 | |
| Diego Perotti | AS Rome | 8 | 7 | |
| 43 | | Valter Birsa | Chievo Verona | 7 | 0 |
| Mattia Caldara | Atalanta Bergame | 7 | 0 | |
| Diego Farias | Cagliari Calcio | 7 | 2 | |
| João Pedro | Cagliari Calcio | 7 | 1 | |
| Mario Mandžukić | Juventus | 7 | 0 | |
| Marco Sau | Cagliari Calcio | 7 | 0 | |
| Suso | AC Milan | 7 | 0 | |
| 50 | | Éver Banega | Inter Milan | 6 | 0 |
| Daniele Baselli | Torino FC | 6 | 0 | |
| Ahmad Benali | Delfino Pescara | 6 | 0 | |
| Antonio Candreva | Inter Milan | 6 | 0 | |
| Franck Kessié | Atalanta Bergame | 6 | 2 | |
| Jasmin Kurtić | Atalanta Bergame | 6 | 0 | |
 | Levan Mchedlidze | Empoli FC | 6 | 0 | |
| Lorenzo Pellegrini | Sassuolo Calcio | 6 | 1 | |
| Stipe Perica | Udinese Calcio | 6 | 0 | |
| Andrea Rispoli | Palermo FC | 6 | 0 | |
| Simone Verdi | AC Milan | 6 | 0 | |
| 61 | | Marco Benassi | Torino FC | 5 | 0 |
| Domenico Berardi | Sassuolo Calcio | 5 | 2 | |
| Bruno Fernandes | Sampdoria | 5 | 0 | |
| Lucas Castro | Chievo Verona | 5 | 0 | |
| Seko Fofana | Udinese Calcio | 5 | 0 | |
| Remo Freuler | Atalanta Bergame | 5 | 0 | |
| Pietro Iemmello | Sassuolo Calcio | 5 | 1 | |
| Josip Iličič | ACF Fiorentina | 5 | 1 | |
| Jakub Jankto | Udinese Calcio | 5 | 0 | |
| Sami Khedira | Juventus | 5 | 0 | |
| Massimo Maccarone | Empoli FC | 5 | 2 | |
| Arkadiusz Milik | SSC Naples | 5 | 0 | |
| Marco Parolo | Lazio de Rome | 5 | 0 | |
| Mario Pašalić | AC Milan | 5 | 0 | |
| Andrea Petagna | Atalanta Bergame | 5 | 0 | |
| Miralem Pjanić | Juventus | 5 | 0 | |
| Matteo Politano | Sassuolo Calcio | 5 | 2 | |
| Piotr Zieliński | SSC Naples | 5 | 0 | |
| 79 | | Francesco Acerbi | Sassuolo Calcio | 4 | 1 |
| Jean-Christophe Bahebeck | Delfino Pescara | 4 | 0 | |
| Lucas Biglia | Lazio de Rome | 4 | 3 | |
| Marcelo Brozović | Inter Milan | 4 | 0 | |
| Cristian Tello | ACF Fiorentina | 4 | 0 | |
| Rodrigo De Paul | Udinese Calcio | 4 | 0 | |
| Daniele De Rossi | AS Rome | 4 | 2 | |
| Federico Di Francesco | Bologna FC | 4 | 0 | |
| Felipe Anderson | Lazio de Rome | 4 | 1 | |
| Gerard Deulofeu | AC Milan | 4 | 0 | |
| Sergej Milinković-Savić | Lazio de Rome | 4 | 0 | |
| Robin Quaison | Palermo FC | 4 | 0 | |
| Antonino Ragusa | Sassuolo Calcio | 4 | 0 | |
| Riccardo Saponara | ACF Fiorentina | 4 | 0 | |
| Kevin Strootman | AS Rome | 4 | 0 | |
| 94 | | Alex Sandro | Juventus | 3 | 0 |
| Giacomo Bonaventura | AC Milan | 3 | 0 | |
| Leonardo Bonucci | Juventus | 3 | 0 | |
| Federico Chiesa | ACF Fiorentina | 3 | 0 | |
| Ivaylo Chochev | Palermo FC | 3 | 0 | |
| Bryan Cristante | Atalanta Bergame | 3 | 0 | |
| Danilo D'Ambrosio | Inter Milan | 3 | 0 | |
| Omar El Kaddouri | Empoli FC | 3 | 0 | |
 | Gian Marco Ferrari | FC Crotone | 3 | 0 | |
| Manolo Gabbiadini | SSC Naples | 3 | 1 | |
| Artur Ioniță | Cagliari Calcio | 3 | 0 | |
| João Mário | Inter Milan | 3 | 0 | |
| Juraj Kucka | AC Milan | 3 | 0 | |
| Senad Lulić | Lazio de Rome | 3 | 0 | |
| Andrea Masiello | Atalanta Bergame | 3 | 0 | |
| Riccardo Meggiorini | Chievo Verona | 3 | 0 | |
| Federico Melchiorri | Cagliari Calcio | 3 | 0 | |
| M'Baye Niang | AC Milan | 3 | 1 | |
| Olivier Ntcham | Genoa CFC | 3 | 0 | |
| Simy Nwankwo | FC Crotone | 3 | 0 | |
| Lucas Ocampos | AC Milan | 3 | 1 | |
| Goran Pandev | Genoa CFC | 3 | 0 | |
| Leandro Paredes | AS Rome | 3 | 0 | |
| Leonardo Pavoletti | Genoa CFC | 3 | 0 | |
| Manuel Pucciarelli | Empoli FC | 3 | 1 | |
| Luca Rigoni | Genoa CFC | 3 | 0 | |
| Adrian Stoian | FC Crotone | 3 | 0 | |
| Saphir Taïder | Bologna FC | 3 | 0 | |
| Marcello Trotta | Sassuolo Calcio | 3 | 1 | |
| Matías Vecino | ACF Fiorentina | 3 | 0 | |
| 124 | | Afriyie Acquah | Torino FC | 2 | 0 |
| Ricardo Álvarez | Sampdoria | 2 | 0 | |
| Davide Astori | ACF Fiorentina | 2 | 0 | |
| Milan Badelj | ACF Fiorentina | 2 | 0 | |
| Édgar Barreto | Sampdoria | 2 | 0 | |
| Bruno Peres | AS Rome | 2 | 0 | |
| Hugo Campagnaro | Delfino Pescara | 2 | 0 | |
| Alberto Cerri | Juventus | 2 | 0 | |
| Giorgio Chiellini | Juventus | 2 | 0 | |
| Vlad Chiricheş | SSC Naples | 2 | 0 | |
| Andrea Costa | Empoli FC | 2 | 0 | |
| Juan Cuadrado | Juventus | 2 | 0 | |
| Dani Alves | Juventus | 2 | 0 | |
| Danilo | Udinese Calcio | 2 | 0 | |
| Jonathan de Guzmán | Chievo Verona | 2 | 1 | |
| Stefan de Vrij | Lazio de Rome | 2 | 0 | |
| Daniele Dessena | Cagliari Calcio | 2 | 0 | |
| Davide Di Gennaro | Cagliari Calcio | 2 | 0 | |
| Federico Fazio | AS Rome | 2 | 0 | |
| Roberto Gagliardini | Atalanta Bergame | 2 | 0 | |
| Edoardo Goldaniga | Palermo FC | 2 | 0 | |
| Oscar Hiljemark | Genoa CFC | 2 | 0 | |
| Wesley Hoedt | Lazio de Rome | 2 | 0 | |
| Kalidou Koulibaly | SSC Naples | 2 | 0 | |
| Rade Krunić | Empoli FC | 2 | 0 | |
| Darko Lazović | Genoa CFC | 2 | 0 | |
| Manuel Locatelli | AC Milan | 2 | 0 | |
| Maxi López | Torino FC | 2 | 0 | |
| Rey Manaj | Inter Milan | 2 | 0 | |
| Alessandro Murgia | Lazio de Rome | 2 | 0 | |
| Andrea Nalini | FC Crotone | 2 | 0 | |
| Nikola Ninković | Genoa CFC | 2 | 0 | |
| Gabriel Paletta | AC Milan | 2 | 0 | |
| Raffaele Palladino | Genoa CFC | 2 | 1 | |
| Manuel Pasqual | Empoli FC | 2 | 1 | |
| Stefan Radu | Lazio de Rome | 2 | 0 | |
| Federico Ricci | AS Rome | 2 | 1 | |
| Daniele Rugani | Juventus | 2 | 0 | |
| Lorenzo Tonelli | SSC Naples | 2 | 0 | |
| Francesco Totti | AS Rome | 2 | 2 | |
| Federico Viviani | Bologna FC | 2 | 0 | |
| Mauro Zárate | ACF Fiorentina | 2 | 0 | |
| 166 | | Claud Adjapong | Sassuolo Calcio | 1 | 0 |
| Arlind Ajeti | Torino FC | 1 | 0 | |
| Haitam Aleesami | Palermo FC | 1 | 0 | |
| Allan | SSC Naples | 1 | 0 | |
| Marco Andreolli | Inter Milan | 1 | 0 | |
| Gabriele Angella | Udinese Calcio | 1 | 0 | |
| Luca Antei | Sassuolo Calcio | 1 | 0 | |
| Alberto Aquilani | Sassuolo Calcio | 1 | 0 | |
| Andrija Balić | Udinese Calcio | 1 | 0 | |
| Dušan Basta | Lazio de Rome | 1 | 0 | |
| Samuel Bastien | Chievo Verona | 1 | 0 | |
| Giuseppe Bellusci | Empoli FC | 1 | 0 | |
| Medhi Benatia | Juventus | 1 | 0 | |
| Andrea Bertolacci | AC Milan | 1 | 0 | |
| Cristiano Biraghi | Delfino Pescara | 1 | 1 | |
| Borja Valero | ACF Fiorentina | 1 | 0 | |
| Lucas Boyé | Torino FC | 1 | 0 | |
| Gastón Brugman | Delfino Pescara | 1 | 0 | |
| Bruno Alves | Cagliari Calcio | 1 | 0 | |
| Bruno Henrique | Palermo FC | 1 | 0 | |
| Fabrizio Cacciatore | Chievo Verona | 1 | 0 | |
| Paolo Cannavaro | Sassuolo Calcio | 1 | 0 | |
| Marco Capuano | Cagliari Calcio | 1 | 0 | |
| Danilo Cataldi | Genoa CFC | 1 | 0 | |
| Federico Ceccherini | FC Crotone | 1 | 0 | |
| Boštjan Cesar | Chievo Verona | 1 | 0 | |
| Luca Crecco | Lazio de Rome | 1 | 0 | |
| Daniele Croce | Empoli FC | 1 | 0 | |
| Marco D'Alessandro | Atalanta Bergame | 1 | 0 | |
| Lorenzo De Silvestri | Sampdoria | 1 | 0 | |
| Alessandro Diamanti | Palermo FC | 1 | 0 | |
| Alfred Duncan | Sassuolo Calcio | 1 | 0 | |
| Felipe | Udinese Calcio | 1 | 0 | |
| Matías Fernández | AC Milan | 1 | 0 | |
| Gabriel Barbosa | Inter Milan | 1 | 0 | |
| Serge Gakpé | Chievo Verona | 1 | 0 | |
| Alessandro Gamberini | Chievo Verona | 1 | 0 | |
| Emanuele Giaccherini | SSC Naples | 1 | 0 | |
| Massimo Gobbi | Chievo Verona | 1 | 0 | |
| Giancarlo González | Palermo FC | 1 | 0 | |
| Alberto Grassi | Atalanta Bergame | 1 | 0 | |
| Kwang-song Han | Cagliari Calcio | 1 | 0 | |
| Filip Helander | Bologna FC | 1 | 0 | |
| Hernanes | Juventus | 1 | 0 | |
| Keisuke Honda | AC Milan | 1 | 0 | |
| Mauricio Isla | Cagliari Calcio | 1 | 0 | |
| Juan Iturbe | AS Rome | 1 | 0 | |
| Mato Jajalo | Palermo FC | 1 | 0 | |
| Moise Kean | Juventus | 1 | 0 | |
| Geoffrey Kondogbia | Inter Milan | 1 | 0 | |
| Ladislav Krejčí | Bologna FC | 1 | 1 | |
| Diego Laxalt | Genoa CFC | 1 | 0 | |
| Mario Lemina | Juventus | 1 | 0 | |
| Stephan Lichtsteiner | Juventus | 1 | 0 | |
| Karol Linetty | Sampdoria | 1 | 0 | |
| Cristiano Lombardi | Lazio de Rome | 1 | 0 | |
| Luis Alberto | Lazio de Rome | 1 | 0 | |
| Francesco Magnanelli | Sassuolo Calcio | 1 | 0 | |
| Nikola Maksimović | SSC Naples | 1 | 0 | |
| Claudio Marchisio | Juventus | 1 | 0 | |
| Josef Martínez | Torino FC | 1 | 0 | |
| Adam Masina | Bologna FC | 1 | 0 | |
| Luca Mazzitelli | Sassuolo Calcio | 1 | 0 | |
| Ledian Memushaj | Delfino Pescara | 1 | 0 | |
| Alexandru Mitriţă | Delfino Pescara | 1 | 0 | |
| Emiliano Moretti | Torino FC | 1 | 0 | |
| Sulley Ali Muntari | Delfino Pescara | 1 | 0 | |
| Robert Murić | Delfino Pescara | 1 | 0 | |
| Simone Padoin | Cagliari Calcio | 1 | 0 | |
| Pietro Pellegri | Genoa CFC | 1 | 0 | |
| Federico Peluso | Sassuolo Calcio | 1 | 0 | |
| Mauricio Pinilla | Atalanta Bergame | 1 | 1 | |
| Fabio Pisacane | Cagliari Calcio | 1 | 0 | |
| Dennis Praet | Sampdoria | 1 | 0 | |
| Erick Pulgar | Bologna FC | 1 | 0 | |
| Nicola Rigoni | Chievo Verona | 1 | 0 | |
| Gonzalo Rodríguez | ACF Fiorentina | 1 | 0 | |
| Marcus Rohdén | FC Crotone | 1 | 0 | |
| Alessio Romagnoli | AC Milan | 1 | 0 | |
| Aleandro Rosi | Genoa CFC | 1 | 0 | |
| Luca Rossettini | Bologna FC | 1 | 0 | |
| Roland Sallai | Palermo FC | 1 | 0 | |
| Mario Sampirisi | FC Crotone | 1 | 0 | |
| Carlos Sánchez | ACF Fiorentina | 1 | 0 | |
| Stefano Sensi | Sassuolo Calcio | 1 | 0 | |
| Mame Thiam | Empoli FC | 1 | 0 | |
| Aleksandar Tonev | FC Crotone | 1 | 0 | |
| Vasilios Torosidis | AS Rome | 1 | 0 | |
| Aleksandar Trajkovski | Palermo FC | 1 | 0 | |
| Wallace | Lazio de Rome | 1 | 0 | |
| Miha Zajc | Empoli FC | 1 | 0 | |
| Cristián Zapata | AC Milan | 1 | 0 | |
| Davide Zappacosta | Torino FC | 1 | 0 |
