| # | Nom | Équipe | Buts | Pén | |
|---|---|---|---|---|---|
| 1 |  | Victor Osimhen | SSC Naples | 26 | 2 |
| 2 |  | Lautaro Martínez | Inter Milan | 21 | 1 |
| 3 |  | Boulaye Dia | US Salernitana 1919 | 16 | 1 |
| 4 |  | Rafael Leão | AC Milan | 15 | 0 |
| 5 | | Olivier Giroud | AC Milan | 13 | 3 |
 | Ademola Lookman | Atalanta Bergame | 13 | 3 | |
 | M'Bala Nzola | Spezia Calcio | 13 | 3 | |
| 8 |  | Domenico Berardi | Sassuolo Calcio | 12 | 7 |
 | Paulo Dybala | AS Rome | 12 | 5 | |
 | Ciro Immobile | Lazio de Rome | 12 | 4 | |
| Khvicha Kvaratskhelia | SSC Naples | 12 | 2 | |
 | Antonio Sanabria | Torino FC | 12 | 1 | |
| 13 |  | Riccardo Orsolini | Bologna FC | 11 | 3 |
| 14 | | Marko Arnautović | Bologna FC | 10 | 3 |
 | Beto | Udinese Calcio | 10 | 1 | |
| Teun Koopmeiners | Atalanta Bergame | 10 | 2 | |
| Romelu Lukaku | Inter Milan | 10 | 2 | |
 | Dušan Vlahović | Juventus | 10 | 2 | |
| Mattia Zaccagni | Lazio de Rome | 10 | 1 | |
| 20 | | Edin Džeko | Inter Milan | 9 | 0 |
| Felipe Anderson | Lazio de Rome | 9 | 0 | |
| Rasmus Højlund | Atalanta Bergame | 9 | 0 | |
| Sergej Milinković-Savić | Lazio de Rome | 9 | 0 | |
| 24 | | Tammy Abraham | AS Rome | 8 | 0 |
 | Arthur Cabral | ACF Fiorentina | 8 | 2 | |
 | Daniel Ciofani | US Cremonese | 8 | 3 | |
 | Gabriel Strefezza | US Lecce | 8 | 2 | |
| Adrien Rabiot | Juventus | 8 | 0 | |
| 29 | | Antonio Candreva | US Salernitana 1919 | 7 | 0 |
| Stephan El Shaarawy | AS Rome | 7 | 0 | |
| Lewis Ferguson | Bologna FC | 7 | 0 | |
| Davide Frattesi | Sassuolo Calcio | 7 | 0 | |
 | Manolo Gabbiadini | Sampdoria | 7 | 0 | |
| Armand Laurienté | Sassuolo Calcio | 7 | 1 | |
| Arkadiusz Milik | Juventus | 7 | 0 | |
| David Okereke | US Cremonese | 7 | 1 | |
| 37 | | Nicolò Barella | Inter Milan | 6 | 0 |
| Brahim Díaz | AC Milan | 6 | 0 | |
 | Nicolò Cambiaghi | Empoli FC | 6 | 0 | |
| Francesco Caputo | Empoli FC | 6 | 2 | |
 | Carlos Augusto | AC Monza | 6 | 0 | |
| Assan Ceesay | US Lecce | 6 | 1 | |
| Patrick Ciurria | AC Monza | 6 | 0 | |
| Cyriel Dessers | US Cremonese | 6 | 0 | |
| Eljif Elmas | SSC Naples | 6 | 1 | |
| Nicolás González | ACF Fiorentina | 6 | 2 | |
| Luka Jović | ACF Fiorentina | 6 | 0 | |
| Moise Kean | Juventus | 6 | 0 | |
| Luis Alberto | Lazio de Rome | 6 | 1 | |
| Stefan Posch | Bologna FC | 6 | 0 | |
| 51 | | Giacomo Bonaventura | ACF Fiorentina | 5 | 0 |
| Gianluca Caprari | AC Monza | 5 | 1 | |
| Lorenzo Colombo | AC Milan | 5 | 1 | |
| Dany Mota | AC Monza | 5 | 0 | |
| Sandi Lovrič | Udinese Calcio | 5 | 0 | |
| Junior Messias | AC Milan | 5 | 0 | |
| Mario Pašalić | Atalanta Bergame | 5 | 0 | |
| Roberto Pereyra | Udinese Calcio | 5 | 0 | |
| Matteo Pessina | AC Monza | 5 | 3 | |
| Andrea Pinamonti | Sassuolo Calcio | 5 | 1 | |
| Lazar Samardžić | Udinese Calcio | 5 | 0 | |
| Simone Verdi | Torino FC | 5 | 1 | |
| Nikola Vlašić | Torino FC | 5 | 0 | |
| 64 | | Tommaso Baldanzi | Empoli FC | 4 | 0 |
| Bremer | Juventus | 4 | 0 | |
| Andrea Colpani | AC Monza | 4 | 0 | |
| Ángel Di María | Juventus | 4 | 1 | |
| Federico Dimarco | Inter Milan | 4 | 0 | |
| Theo Hernández | AC Milan | 4 | 1 | |
| Jonathan Ikoné | ACF Fiorentina | 4 | 0 | |
| Yann Karamoh | Torino FC | 4 | 0 | |
| Christian Kouamé | ACF Fiorentina | 4 | 0 | |
 | Darko Lazović | Hellas Verona | 4 | 0 | |
| Matheus Henrique | Sassuolo Calcio | 4 | 0 | |
| Aleksey Miranchuk | Atalanta Bergame | 4 | 0 | |
| Pedro | Lazio de Rome | 4 | 0 | |
| Lorenzo Pellegrini | AS Rome | 4 | 2 | |
| Andrea Petagna | SSC Naples | 4 | 1 | |
| Krzysztof Piątek | US Salernitana 1919 | 4 | 1 | |
| Nicola Sansone | Bologna FC | 4 | 0 | |
| Riccardo Saponara | ACF Fiorentina | 4 | 0 | |
| Giovanni Simeone | SSC Naples | 4 | 0 | |
| Tonny Vilhena | US Salernitana 1919 | 4 | 0 | |
| Davide Zappacosta | Atalanta Bergame | 4 | 0 | |
| 85 | | Frank Anguissa | SSC Naples | 3 | 0 |
| Musa Barrow | Bologna FC | 3 | 0 | |
| Federico Baschirotto | US Lecce | 3 | 0 | |
| Jaka Bijol | Udinese Calcio | 3 | 0 | |
| Marcelo Brozović | Inter Milan | 3 | 0 | |
| Hakan Çalhanoğlu | Inter Milan | 3 | 1 | |
| Joaquín Correa | Inter Milan | 3 | 0 | |
| Lassana Coulibaly | US Salernitana 1919 | 3 | 0 | |
| Danilo | Juventus | 3 | 0 | |
| Marten de Roon | Atalanta Bergame | 3 | 0 | |
| Giovanni Di Lorenzo | SSC Naples | 3 | 0 | |
| Nicolás Domínguez | Bologna FC | 3 | 0 | |
| Filip Đuričić | Sampdoria | 3 | 0 | |
| Nicolò Fagioli | Juventus | 3 | 0 | |
| Robin Gosens | Inter Milan | 3 | 0 | |
| Ibañez | AS Rome | 3 | 0 | |
| Filip Kostić | Juventus | 3 | 0 | |
| Hirving Lozano | SSC Naples | 3 | 1 | |
| Joakim Mæhle | Atalanta Bergame | 3 | 0 | |
| Henrikh Mkhitaryan | Inter Milan | 3 | 0 | |
| Luis Muriel | Atalanta Bergame | 3 | 1 | |
| Cyril Ngonge | Hellas Verona | 3 | 0 | |
| Rémi Oudin | US Lecce | 3 | 0 | |
| Matteo Politano | SSC Naples | 3 | 2 | |
| Ante Rebić | AC Milan | 3 | 0 | |
| Stefano Sensi | AC Monza | 3 | 0 | |
| Chris Smalling | AS Rome | 3 | 0 | |
| Frank Tsadjout | US Cremonese | 3 | 0 | |
| Destiny Udogie | Udinese Calcio | 3 | 0 | |
| Daniele Verde | Spezia Calcio | 3 | 1 | |
| Piotr Zieliński | SSC Naples | 3 | 0 | |
| 116 | | Tommaso Augello | Sampdoria | 2 | 0 |
| Nedim Bajrami | Empoli FC | 2 | 0 | |
| Lameck Banda | US Lecce | 2 | 0 | |
| Filippo Bandinelli | Empoli FC | 2 | 0 | |
| Antonín Barák | ACF Fiorentina | 2 | 0 | |
| Simone Bastoni | Spezia Calcio | 2 | 0 | |
| Ismaël Bennacer | AC Milan | 2 | 0 | |
| Cristiano Biraghi | ACF Fiorentina | 2 | 0 | |
| Jérémie Boga | Atalanta Bergame | 2 | 0 | |
| Federico Bonazzoli | Sampdoria | 2 | 0 | |
| Luca Caldirola | AC Monza | 2 | 0 | |
| Gaetano Castrovilli | ACF Fiorentina | 2 | 0 | |
| Federico Ceccherini | Hellas Verona | 2 | 0 | |
| Federico Chiesa | Juventus | 2 | 0 | |
| Grégoire Defrel | Sassuolo Calcio | 2 | 0 | |
| Fabio Depaoli | Sampdoria | 2 | 0 | |
| Federico Di Francesco | US Lecce | 2 | 0 | |
| Josh Doig | Hellas Verona | 2 | 0 | |
| Tyronne Ebuehi | Empoli FC | 2 | 0 | |
| Kingsley Ehizibue | Udinese Calcio | 2 | 0 | |
| Davide Faraoni | Hellas Verona | 2 | 0 | |
| Adolfo Gaich | Hellas Verona | 2 | 0 | |
| Gerard Deulofeu | Udinese Calcio | 2 | 0 | |
| Emmanuel Gyasi | Spezia Calcio | 2 | 0 | |
| Abdou Harroui | Sassuolo Calcio | 2 | 0 | |
| Thomas Henry | Hellas Verona | 2 | 0 | |
| Ivan Ilić | Torino FC | 2 | 0 | |
| Grigoris Kastanos | US Salernitana 1919 | 2 | 0 | |
| Min-jae Kim | SSC Naples | 2 | 0 | |
| Sam Lammers | Atalanta Bergame | 2 | 0 | |
| Saša Lukić | Torino FC | 2 | 1 | |
| Sebastiano Luperto | Empoli FC | 2 | 0 | |
| Charalampos Lykogiannis | Bologna FC | 2 | 0 | |
| Daniel Maldini | AC Milan | 2 | 0 | |
| Rolando Mandragora | ACF Fiorentina | 2 | 0 | |
| Răzvan Marin | Empoli FC | 2 | 0 | |
| Adam Masina | Udinese Calcio | 2 | 0 | |
| Nemanja Matić | AS Rome | 2 | 0 | |
| Pasquale Mazzocchi | US Salernitana 1919 | 2 | 0 | |
| Nikola Milenković | ACF Fiorentina | 2 | 0 | |
| Ilija Nestorovski | Udinese Calcio | 2 | 0 | |
| Mathías Olivera | SSC Naples | 2 | 0 | |
| Divock Origi | AC Milan | 2 | 0 | |
| Fabiano Parisi | Empoli FC | 2 | 0 | |
| Pietro Pellegri | Torino FC | 2 | 0 | |
| Nehuén Pérez | Udinese Calcio | 2 | 0 | |
| Roberto Piccoli | Empoli FC | 2 | 0 | |
| Lorenzo Pirola | US Salernitana 1919 | 2 | 0 | |
| Tommaso Pobega | AC Milan | 2 | 0 | |
| Nemanja Radonjić | Torino FC | 2 | 0 | |
| Giacomo Raspadori | SSC Naples | 2 | 0 | |
| Samuele Ricci | Torino FC | 2 | 0 | |
| Rodrigo Becão | Udinese Calcio | 2 | 0 | |
| Alessio Romagnoli | Lazio de Rome | 2 | 0 | |
| Amir Rrahmani | SSC Naples | 2 | 0 | |
| Abdelhamid Sabiri | Sampdoria | 2 | 1 | |
| Alexis Saelemaekers | AC Milan | 2 | 0 | |
| Martín Satriano | Empoli FC | 2 | 0 | |
| Giorgio Scalvini | Atalanta Bergame | 2 | 0 | |
| Leonardo Sernicola | US Cremonese | 2 | 0 | |
| Wilfried Singo | Torino FC | 2 | 0 | |
| Kristian Thorstvedt | Sassuolo Calcio | 2 | 0 | |
| Rafael Tolói | Atalanta Bergame | 2 | 0 | |
| Sandro Tonali | AC Milan | 2 | 0 | |
| Emanuele Valeri | US Cremonese | 2 | 0 | |
| Matías Vecino | Lazio de Rome | 2 | 0 | |
| Georginio Wijnaldum | AS Rome | 2 | 0 | |
| Nicola Zalewski | AS Rome | 2 | 0 | |
| Alessandro Zanoli | Sampdoria | 2 | 0 | |
| Duván Zapata | Atalanta Bergame | 2 | 0 | |
| Joshua Zirkzee | Bologna FC | 2 | 0 | |
| 187 | | Michel Aebischer | Bologna FC | 1 | 0 |
| Ola Aina | Torino FC | 1 | 0 | |
| Jean-Daniel Akpa-Akpro | Empoli FC | 1 | 0 | |
| Agustín Álvarez | Sassuolo Calcio | 1 | 0 | |
| Bruno Amione | Sampdoria | 1 | 0 | |
| Janis Antiste | Spezia Calcio | 1 | 0 | |
| Tolgay Arslan | Udinese Calcio | 1 | 0 | |
| Fodé Ballo-Touré | AC Milan | 1 | 0 | |
| Toma Bašić | Lazio de Rome | 1 | 0 | |
| Matteo Bianchetti | US Cremonese | 1 | 0 | |
| Alexis Blin | US Lecce | 1 | 0 | |
| Leonardo Bonucci | Juventus | 1 | 0 | |
| Erik Botheim | US Salernitana 1919 | 1 | 0 | |
| Mehdi Bourabia | Spezia Calcio | 1 | 0 | |
| Edoardo Bove | AS Rome | 1 | 0 | |
| Cristian Buonaiuto | US Cremonese | 1 | 1 | |
| Alessandro Buongiorno | Torino FC | 1 | 0 | |
| Davide Calabria | AC Milan | 1 | 0 | |
| Nicolò Casale | Lazio de Rome | 1 | 0 | |
| Omar Colley | Sampdoria | 1 | 0 | |
| Bryan Cristante | AS Rome | 1 | 0 | |
| Juan Cuadrado | Juventus | 1 | 0 | |
| Matteo Darmian | Inter Milan | 1 | 0 | |
| Paweł Dawidowicz | Hellas Verona | 1 | 0 | |
| Lorenzo De Silvestri | Bologna FC | 1 | 0 | |
| Stefan de Vrij | Inter Milan | 1 | 0 | |
| Merih Demiral | Atalanta Bergame | 1 | 0 | |
| Mattia Destro | Empoli FC | 1 | 0 | |
| Koffi Djidji | Torino FC | 1 | 0 | |
| Dodô | ACF Fiorentina | 1 | 0 | |
| Giulio Donati | AC Monza | 1 | 0 | |
| Denzel Dumfries | Inter Milan | 1 | 0 | |
| Alfred Duncan | ACF Fiorentina | 1 | 0 | |
| Milan Đurić | Hellas Verona | 1 | 0 | |
| Éderson | Atalanta Bergame | 1 | 0 | |
| Salvatore Esposito | Spezia Calcio | 1 | 0 | |
| Federico Fazio | US Salernitana 1919 | 1 | 0 | |
| Gian Marco Ferrari | Sassuolo Calcio | 1 | 0 | |
| Gianluca Gaetano | SSC Naples | 1 | 0 | |
| Pablo Galdames | US Cremonese | 1 | 0 | |
| Paolo Ghiglione | US Cremonese | 1 | 0 | |
| Koray Günter | Sampdoria | 1 | 0 | |
| Christian Gytkjær | AC Monza | 1 | 0 | |
| Nicolas Haas | Empoli FC | 1 | 0 | |
| Hans Hateboer | Atalanta Bergame | 1 | 0 | |
| Emil Holm | Spezia Calcio | 1 | 0 | |
| Elseid Hysaj | Lazio de Rome | 1 | 0 | |
| Zlatan Ibrahimović | AC Milan | 1 | 1 | |
| Samuel Iling | Juventus | 1 | 0 | |
| Armando Izzo | Torino FC | 1 | 0 | |
| Jesé | Sampdoria | 1 | 0 | |
| Joan Gonzàlez | US Lecce | 1 | 0 | |
| Juan Jesus | SSC Naples | 1 | 0 | |
| Yayah Kallon | Hellas Verona | 1 | 0 | |
| Pierre Kalulu | AC Milan | 1 | 0 | |
| Giorgos Kyriakopoulos | Bologna FC | 1 | 0 | |
| Kevin Lasagna | Hellas Verona | 1 | 0 | |
| Mehdi Léris | Sampdoria | 1 | 0 | |
| Karol Linetty | Torino FC | 1 | 0 | |
| Stanislav Lobotka | SSC Naples | 1 | 0 | |
| Luka Lochoshvili | US Cremonese | 1 | 0 | |
| Ruslan Malinovskiy | Atalanta Bergame | 1 | 0 | |
| Gianluca Mancini | AS Rome | 1 | 0 | |
| Marcos Antônio | Lazio de Rome | 1 | 0 | |
| Lucas Martínez Quarta | ACF Fiorentina | 1 | 0 | |
| Weston McKennie | Juventus | 1 | 0 | |
| Nikola Moro | Bologna FC | 1 | 0 | |
| Tanguy Ndombèlé | SSC Naples | 1 | 0 | |
| Hans Nicolussi Caviglia | US Salernitana 1919 | 1 | 0 | |
| Dimitrios Nikolaou | Spezia Calcio | 1 | 0 | |
| Pablo Marí | AC Monza | 1 | 0 | |
| José Palomino | Atalanta Bergame | 1 | 0 | |
| Leandro Paredes | Juventus | 1 | 0 | |
| Charles Pickel | US Cremonese | 1 | 0 | |
| Fabio Quagliarella | Sampdoria | 1 | 0 | |
| Filippo Ranocchia | Juventus | 1 | 0 | |
| Arkadiusz Reca | Spezia Calcio | 1 | 0 | |
| Luka Romero | Lazio de Rome | 1 | 0 | |
| Nicolò Rovella | Juventus | 1 | 0 | |
| Eldor Shomurodov | AS Rome | 1 | 0 | |
| Ola Solbakken | AS Rome | 1 | 0 | |
| Roberto Soriano | Bologna FC | 1 | 0 | |
| Matías Soulé | Juventus | 1 | 0 | |
| Leonardo Spinazzola | AS Rome | 1 | 0 | |
| Isaac Success | Udinese Calcio | 1 | 0 | |
| Aleksa Terzić | ACF Fiorentina | 1 | 0 | |
| Fikayo Tomori | AC Milan | 1 | 0 | |
| William Troost-Ekong | US Salernitana 1919 | 1 | 0 | |
| Johan Vásquez | US Cremonese | 1 | 0 | |
| Emanuel Vignato | Bologna FC | 1 | 0 | |
| Cristian Volpato | AS Rome | 1 | 0 | |
| Przemysław Wiśniewski | Spezia Calcio | 1 | 0 | |
| Nicolò Zaniolo | AS Rome | 1 | 0 | |
| Marvin Zeegelaar | Udinese Calcio | 1 | 0 | |
| Nadir Zortea | Atalanta Bergame | 1 | 0 |
