| # | Équipe | Équipe | J | G | N | P | Buts | Diff | PTS | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Inter Milan | Inter | 38 | 29 | 7 | 2 | 89:22 | 67 | 94 |
| 2 |  | AC Milan | AC Milan | 38 | 22 | 9 | 7 | 76:49 | 27 | 75 |
| 3 |  | Juventus | Juventus | 38 | 19 | 14 | 5 | 54:31 | 23 | 71 |
| 4 |  | Atalanta Bergame | Atalanta | 38 | 21 | 6 | 11 | 72:42 | 30 | 69 |
| 5 |  | Bologna FC | Bologna | 38 | 18 | 14 | 6 | 54:32 | 22 | 68 |
| 6 |  | AS Rome | AS Rome | 38 | 18 | 9 | 11 | 65:46 | 19 | 63 |
| 7 |  | Lazio de Rome | Lazio | 38 | 18 | 7 | 13 | 49:39 | 10 | 61 |
| 8 |  | ACF Fiorentina | Fiorentina | 38 | 17 | 9 | 12 | 61:46 | 15 | 60 |
| 9 |  | Torino FC | Torino FC | 38 | 13 | 14 | 11 | 36:36 | 0 | 53 |
| 10 |  | SSC Naples | Naples | 38 | 13 | 14 | 11 | 55:48 | 7 | 53 |
| 11 |  | Genoa CFC | Genoa CFC | 38 | 12 | 13 | 13 | 45:45 | 0 | 49 |
| 12 |  | AC Monza | AC Monza | 38 | 11 | 12 | 15 | 39:51 | -12 | 45 |
| 13 |  | Hellas Verona | Hellas Verona | 38 | 9 | 11 | 18 | 38:51 | -13 | 38 |
| 14 |  | US Lecce | Lecce | 38 | 8 | 14 | 16 | 32:54 | -22 | 38 |
| 15 |  | Udinese Calcio | Udinese | 38 | 6 | 19 | 13 | 37:53 | -16 | 37 |
| 16 |  | Cagliari Calcio | Cagliari | 38 | 8 | 12 | 18 | 42:68 | -26 | 36 |
| 17 |  | Empoli FC | Empoli | 38 | 9 | 9 | 20 | 29:54 | -25 | 36 |
| 18 |  | Frosinone Calcio | Frosinone | 38 | 8 | 11 | 19 | 44:69 | -25 | 35 |
| 19 |  | Sassuolo Calcio | Sassuolo | 38 | 7 | 9 | 22 | 43:75 | -32 | 30 |
| 20 |  | US Salernitana 1919 | Salernitana | 38 | 2 | 11 | 25 | 32:81 | -49 | 17 |
| # | Nom | Équipe | Buts | Pén | |
|---|---|---|---|---|---|
| 1 | | Lautaro Martínez | Inter Milan | 24 | 2 |
| 2 | | Dušan Vlahović | Juventus | 16 | 2 |
| 3 | | Olivier Giroud | AC Milan | 15 | 4 |
| Victor Osimhen | SSC Naples | 15 | 3 | |
| 5 | | Albert Guðmundsson | Genoa CFC | 14 | 4 |
| 6 | | Hakan Çalhanoğlu | Inter Milan | 13 | 10 |
| Paulo Dybala | AS Rome | 13 | 7 | |
| Romelu Lukaku | AS Rome | 13 | 0 | |
| Marcus Thuram | Inter Milan | 13 | 0 | |
| Duván Zapata | Torino FC | 13 | 0 | |
| 11 | | Nicolás González | ACF Fiorentina | 12 | 1 |
| Teun Koopmeiners | Atalanta Bergame | 12 | 2 | |
| Christian Pulišić | AC Milan | 12 | 0 | |
| Gianluca Scamacca | Atalanta Bergame | 12 | 0 | |
| 15 | | Khvicha Kvaratskhelia | SSC Naples | 11 | 0 |
