| # | Nom | Équipe | Buts | Pén | |
|---|---|---|---|---|---|
| 1 |  | Artem Dovbyk | Girona FC | 19 | 5 |
| 2 |  | Jude Bellingham | Real Madrid | 17 | 1 |
 | Alexander Sørloth | Villarreal CF | 17 | 0 | |
| 4 |  | Ante Budimir | CA Osasuna | 16 | 3 |
 | Robert Lewandowski | FC Barcelone | 16 | 3 | |
| 6 |  | Borja Mayoral | Getafe CF | 15 | 4 |
| 7 |  | Álvaro Morata | Atlético de Madrid | 14 | 0 |
 | Guruzeta | Athletic Bilbao | 14 | 0 | |
| 9 | | Antoine Griezmann | Atlético de Madrid | 13 | 4 |
 | Hugo Duro | Valence CF | 13 | 0 | |
| Vinícius Junior | Real Madrid | 13 | 1 | |
| 12 |  | Youssef En-Nesyri | Séville FC | 12 | 0 |
| 13 |  | Jørgen Strand Larsen | RC Celta | 11 | 0 |
 | Myrto Uzuni | Granada CF | 11 | 4 | |
| 15 | | Gerard Moreno | Villarreal CF | 10 | 2 |
| Rodrygo | Real Madrid | 10 | 0 | |
 | Willian José | Betis Séville | 10 | 0 | |
| 18 | | Ángel Correa | Atlético de Madrid | 9 | 1 |
| Iñaki Williams | Athletic Bilbao | 9 | 0 | |
 | Mikel Oyarzabal | Real Sociedad | 9 | 2 | |
 | Samu Omorodion | CD Alavés | 9 | 0 | |
| 22 | | Mason Greenwood | Getafe CF | 8 | 2 |
| Joselu | Real Madrid | 8 | 0 | |
| Sávio | Girona FC | 8 | 0 | |
| Cristhian Stuani | Girona FC | 8 | 0 | |
| 26 | | Ferran Torres | FC Barcelone | 7 | 0 |
| Iago Aspas | RC Celta | 7 | 1 | |
| Isco | Betis Séville | 7 | 2 | |
| João Félix | FC Barcelone | 7 | 0 | |
| Takefusa Kubo | Real Sociedad | 7 | 0 | |
| 31 |  | Abdón | RCD Mallorca | 6 | 0 |
| Álex Berenguer | Athletic Bilbao | 6 | 1 | |
 | Álvaro García | Rayo Vallecano | 6 | 0 | |
| Ayoze Pérez | Betis Séville | 6 | 0 | |
| Bryan Zaragoza | Granada CF | 6 | 1 | |
| José Morales | Villarreal CF | 6 | 0 | |
 | Kirian Rodríguez | UD Las Palmas | 6 | 0 | |
| Marcos Llorente | Atlético de Madrid | 6 | 0 | |
| Vedat Muriqi | RCD Mallorca | 6 | 1 | |
| Pepelu | Valence CF | 6 | 6 | |
 | Sergio Arribas | UD Almería | 6 | 0 | |
| Viktor Tsygankov | Girona FC | 6 | 0 | |
| 43 | | Lucas Boyé | Granada CF | 5 | 0 |
| Brahim Díaz | Real Madrid | 5 | 0 | |
 | Chris Ramos | Cádiz CF | 5 | 0 | |
| Memphis Depay | Atlético de Madrid | 5 | 0 | |
| Anastasios Douvikas | RC Celta | 5 | 0 | |
| Fermín López | FC Barcelone | 5 | 0 | |
| İlkay Gündoğan | FC Barcelone | 5 | 1 | |
| Iván Martin | Girona FC | 5 | 0 | |
| Jaime Mata | Getafe CF | 5 | 0 | |
| Leo Baptistão | UD Almería | 5 | 0 | |
| Luis Rioja | CD Alavés | 5 | 3 | |
| Portu | Girona FC | 5 | 0 | |
| Raphinha | FC Barcelone | 5 | 0 | |
| 56 | | Ander Barrenetxea | Real Sociedad | 4 | 0 |
| Brais Méndez | Real Sociedad | 4 | 0 | |
| Dani Carvajal | Real Madrid | 4 | 0 | |
| Yangel Herrera | Girona FC | 4 | 0 | |
| Iker Muñoz | CA Osasuna | 4 | 0 | |
| Isaac Romero | Séville FC | 4 | 0 | |
| Isi Palazón | Rayo Vallecano | 4 | 2 | |
| Javier Guerra | Valence CF | 4 | 0 | |
| Lamine Yamal | FC Barcelone | 4 | 0 | |
| Dodi Lukébakio | Séville FC | 4 | 0 | |
| Darwin Machís | Cádiz CF | 4 | 1 | |
| Nemanja Maksimović | Getafe CF | 4 | 0 | |
| Martín Zubimendi | Real Sociedad | 4 | 0 | |
| Mikel Merino | Real Sociedad | 4 | 0 | |
| Nico Williams | Athletic Bilbao | 4 | 0 | |
| Lucas Ocampos | Séville FC | 4 | 1 | |
| Oihan Sancet | Athletic Bilbao | 4 | 0 | |
| Luis Suárez | UD Almería | 4 | 1 | |
| Williot Swedberg | RC Celta | 4 | 0 | |
| 75 | | Adrián Embarba | UD Almería | 3 | 1 |
| Aleix García | Girona FC | 3 | 0 | |
| Antonio Sánchez | RCD Mallorca | 3 | 0 | |
| Benavídez | CD Alavés | 3 | 0 | |
| Dani Parejo | Villarreal CF | 3 | 3 | |
| David López | Girona FC | 3 | 0 | |
| Diego López | Valence CF | 3 | 0 | |
| Eric García | Girona FC | 3 | 0 | |
| Jorge Cuenca | Villarreal CF | 3 | 0 | |
| Juanmi | Cádiz CF | 3 | 0 | |
| Kike García | CD Alavés | 3 | 0 | |
| Kike Salas | Séville FC | 3 | 0 | |
| Latasa | Getafe CF | 3 | 0 | |
| Marc Cardona | UD Las Palmas | 3 | 1 | |
| Moi Gómez | CA Osasuna | 3 | 0 | |
| Munir | UD Las Palmas | 3 | 0 | |
| Raíllo | RCD Mallorca | 3 | 0 | |
| Largie Ramazani | UD Almería | 3 | 0 | |
| Raúl | CA Osasuna | 3 | 0 | |
| Ricard Sánchez | Granada CF | 3 | 0 | |
| Umar Sadiq | Real Sociedad | 3 | 0 | |
| Samuel Lino | Atlético de Madrid | 3 | 0 | |
| Sergi Roberto | FC Barcelone | 3 | 0 | |
| Sergio Camello | Rayo Vallecano | 3 | 0 | |
| Sergio Ramos | Séville FC | 3 | 0 | |
| Aurélien Tchouaméni | Real Madrid | 3 | 0 | |
| Vesga | Athletic Bilbao | 3 | 2 | |
| Roman Yaremchuk | Valence CF | 3 | 0 | |
| Yuri | Athletic Bilbao | 3 | 0 | |
| 104 | | Aitor Ruibal | Betis Séville | 2 | 0 |
| Akieme | UD Almería | 2 | 0 | |
| Alberto Moleiro | UD Las Palmas | 2 | 0 | |
| Alcaraz | Cádiz CF | 2 | 1 | |
| Álex Baena | Villarreal CF | 2 | 0 | |
| André Almeida | Valence CF | 2 | 0 | |
| André Silva | Real Sociedad | 2 | 1 | |
| Ezequiel Ávila | Betis Séville | 2 | 0 | |
| Jonathan Bamba | RC Celta | 2 | 0 | |
| Bebé | Rayo Vallecano | 2 | 1 | |
| Carlos Fernández | Real Sociedad | 2 | 1 | |
| Dani Rodríguez | RCD Mallorca | 2 | 0 | |
| Frenkie de Jong | FC Barcelone | 2 | 0 | |
| Rodrigo De Paul | Atlético de Madrid | 2 | 0 | |
| Assane Diao | Betis Séville | 2 | 0 | |
| Duarte | CD Alavés | 2 | 0 | |
| Édgar González | UD Almería | 2 | 0 | |
| Gonçalo Guedes | Villarreal CF | 2 | 0 | |
| Arda Güler | Real Madrid | 2 | 0 | |
| Ilias Akhomach | Villarreal CF | 2 | 0 | |
| Javi Muñoz | UD Las Palmas | 2 | 0 | |
| João Cancelo | FC Barcelone | 2 | 0 | |
| Jonathan Viera | UD Almería | 2 | 2 | |
| José Arnáiz | CA Osasuna | 2 | 0 | |
| Juanma | UD Las Palmas | 2 | 0 | |
| Érik Lamela | Séville FC | 2 | 0 | |
| Cyle Larin | RCD Mallorca | 2 | 0 | |
| Robin Le Normand | Real Sociedad | 2 | 0 | |
| Florian Lejeune | Rayo Vallecano | 2 | 0 | |
| Choco Lozano | UD Almería | 2 | 0 | |
| Lucas Vázquez | Real Madrid | 2 | 0 | |
| Marc Roca | Betis Séville | 2 | 0 | |
| Luka Modrić | Real Madrid | 2 | 0 | |
| Nahuel Molina | Atlético de Madrid | 2 | 0 | |
| Matija Nastasić | RCD Mallorca | 2 | 0 | |
| Óscar Mingueza | RC Celta | 2 | 0 | |
| Pedri | FC Barcelone | 2 | 0 | |
| Pejiño | UD Las Palmas | 2 | 0 | |
| Facundo Pellistri | Granada CF | 2 | 0 | |
| Rafa Mir | Séville FC | 2 | 0 | |
| Ivan Rakitić | Séville FC | 2 | 0 | |
| Rodrigo Riquelme | Atlético de Madrid | 2 | 0 | |
| Guido Rodríguez | Betis Séville | 2 | 0 | |
| Roger Martí | Cádiz CF | 2 | 0 | |
| Luka Romero | UD Almería | 2 | 0 | |
| Rubén García | CA Osasuna | 2 | 0 | |
| Santi Comesaña | Villarreal CF | 2 | 0 | |
| Unai Gómez | Athletic Bilbao | 2 | 0 | |
| Valery | Girona FC | 2 | 0 | |
| Vítor Roque | FC Barcelone | 2 | 0 | |
| Axel Witsel | Atlético de Madrid | 2 | 0 | |
| 155 | | Adrià Pedrosa | Séville FC | 1 | 0 |
| Aimar Oroz | CA Osasuna | 1 | 1 | |
| Aitor Paredes | Athletic Bilbao | 1 | 0 | |
| Alberto Moreno | Villarreal CF | 1 | 0 | |
| Álex Suárez | UD Las Palmas | 1 | 0 | |
| Tadeo Allende | RC Celta | 1 | 0 | |
| Gastón Álvarez | Getafe CF | 1 | 0 | |
| Andoni Gorosabel | CD Alavés | 1 | 0 | |
| Julián Araujo | UD Las Palmas | 1 | 0 | |
| Ronald Araújo | FC Barcelone | 1 | 0 | |
| Areso | CA Osasuna | 1 | 0 | |
| Sheraldo Becker | Real Sociedad | 1 | 0 | |
| Benito | UD Las Palmas | 1 | 0 | |
| Daley Blind | Girona FC | 1 | 0 | |
| Étienne Capoue | Villarreal CF | 1 | 0 | |
| Carles Aleñá | Getafe CF | 1 | 0 | |
| Carles Pérez | RC Celta | 1 | 0 | |
| Catena | CA Osasuna | 1 | 0 | |
| Andreas Christensen | FC Barcelone | 1 | 0 | |
| Pathé Ciss | Rayo Vallecano | 1 | 0 | |
| Copete | RCD Mallorca | 1 | 0 | |
| Theo Corbeanu | Granada CF | 1 | 0 | |
| Cristian Herrera | UD Las Palmas | 1 | 0 | |
| Dani García | Athletic Bilbao | 1 | 0 | |
| Luca de la Torre | RC Celta | 1 | 0 | |
| De Marcos | Athletic Bilbao | 1 | 0 | |
| Mouctar Diakhaby | Valence CF | 1 | 0 | |
| Gonzalo Escalante | Cádiz CF | 1 | 0 | |
| Abde Ezzalzouli | Betis Séville | 1 | 0 | |
| Radamel Falcao | Rayo Vallecano | 1 | 1 | |
| Fede | Cádiz CF | 1 | 0 | |
| Nabil Fekir | Betis Séville | 1 | 0 | |
| Juan Foyth | Villarreal CF | 1 | 0 | |
| Fran Pérez | Valence CF | 1 | 0 | |
| Gavi | FC Barcelone | 1 | 0 | |
| Gayà | Valence CF | 1 | 0 | |
| Gonzalo Villar | Granada CF | 1 | 0 | |
| Nemanja Gudelj | Séville FC | 1 | 0 | |
| Guevara | CD Alavés | 1 | 0 | |
| Hugo Guillamón | Valence CF | 1 | 0 | |
| Ignasi Miquel | Granada CF | 1 | 0 | |
| Javi Hernández | Cádiz CF | 1 | 0 | |
| Javier Llabrés | RCD Mallorca | 1 | 0 | |
| Jesús Vázquez | Valence CF | 1 | 0 | |
| Johnny Cardoso | Betis Séville | 1 | 0 | |
| Jon Guridi | CD Alavés | 1 | 0 | |
| Jon Pacheco | Real Sociedad | 1 | 0 | |
| Jorge De Frutos | Rayo Vallecano | 1 | 0 | |
| José Ángel | Getafe CF | 1 | 0 | |
| Juan Miranda | Betis Séville | 1 | 0 | |
| Sory Kaba | UD Las Palmas | 1 | 0 | |
| Kaiky | UD Almería | 1 | 0 | |
| Kike Pérez | Rayo Vallecano | 1 | 0 | |
| Jules Koundé | FC Barcelone | 1 | 0 | |
| Toni Kroos | Real Madrid | 1 | 0 | |
| Lucas Pires | Cádiz CF | 1 | 0 | |
| Luis Hernández | Cádiz CF | 1 | 0 | |
| Aïssa Mandi | Villarreal CF | 1 | 0 | |
| Marc Guiu | FC Barcelone | 1 | 0 | |
| Marc Pubill | UD Almería | 1 | 0 | |
| Marezi | UD Almería | 1 | 0 | |
| Bruno Méndez | Granada CF | 1 | 0 | |
| Miguel Gutiérrez | Girona FC | 1 | 0 | |
| Miguel Rubio | Granada CF | 1 | 0 | |
| Stefan Mitrovič | Getafe CF | 1 | 0 | |
| Yerson Mosquera | Villarreal CF | 1 | 0 | |
| Abdul Mumin | Rayo Vallecano | 1 | 0 | |
| Muniain | Athletic Bilbao | 1 | 0 | |
| Nacho Vidal | RCD Mallorca | 1 | 0 | |
| Randy Nteka | Rayo Vallecano | 1 | 1 | |
| Óscar | Rayo Vallecano | 1 | 0 | |
| Óscar | Getafe CF | 1 | 0 | |
| Pablo Fornals | Betis Séville | 1 | 0 | |
| Pablo Ibáñez | CA Osasuna | 1 | 0 | |
| Pedraza | Villarreal CF | 1 | 0 | |
| Pep Chavarría | Rayo Vallecano | 1 | 0 | |
| Germán Pezzella | Betis Séville | 1 | 0 | |
| Raúl de Tomás | Rayo Vallecano | 1 | 1 | |
| Abde Rebbach | CD Alavés | 1 | 0 | |
| Reinildo | Atlético de Madrid | 1 | 0 | |
| Robert Navarro | Cádiz CF | 1 | 0 | |
| Antonio Rüdiger | Real Madrid | 1 | 0 | |
| Ruiz de Galarreta | Athletic Bilbao | 1 | 0 | |
| Samú | RCD Mallorca | 1 | 0 | |
| Sandro | UD Las Palmas | 1 | 0 | |
| Saúl | Atlético de Madrid | 1 | 0 | |
| Saúl Coco | UD Las Palmas | 1 | 0 | |
| Aleksandar Sedlar | CD Alavés | 1 | 0 | |
| Sergi Altimira | Betis Séville | 1 | 0 | |
| Sergi Canós | Valence CF | 1 | 0 | |
| Sergi Cardona | UD Las Palmas | 1 | 0 | |
| Giuliano Simeone | CD Alavés | 1 | 0 | |
| Djibril Sow | Séville FC | 1 | 0 | |
| Carl Starfelt | RC Celta | 1 | 0 | |
| Suso | Séville FC | 1 | 0 | |
| Facundo Tenaglia | CD Alavés | 1 | 0 | |
| Unai García | CA Osasuna | 1 | 0 | |
| Unai López | Rayo Vallecano | 1 | 0 | |
| Unai Núñez | RC Celta | 1 | 0 | |
| Federico Valverde | Real Madrid | 1 | 0 | |
| Villalibre | Athletic Bilbao | 1 | 0 | |
| William Carvalho | Betis Séville | 1 | 0 | |
| Yan Couto | Girona FC | 1 | 0 | |
| Yellu | Getafe CF | 1 | 0 | |
| Arsen Zakharyan | Real Sociedad | 1 | 0 |
