| # | Nom | Équipe | Buts | Pén | |
|---|---|---|---|---|---|
| 1 |  | Pierre-Emerick Aubameyang | Olympique de Marseille | 10 | 3 |
| 2 |  | Romelu Lukaku | AS Rome | 7 | 0 |
| 3 |  | João Pedro | Brighton & Hove Albion | 6 | 4 |
| 4 |  | Victor Boniface | Bayer Leverkusen | 5 | 1 |
 | Michael Gregoritsch | SC Fribourg | 5 | 0 | |
 | Viktor Gyökeres | Sporting CP | 5 | 2 | |
 | Fotis Ioannidis | Panathinaikos | 5 | 2 | |
 | Juninho | Qarabağ FK | 5 | 0 | |
 | Mohammed Kudus | West Ham United | 5 | 0 | |
 | Darwin Núñez | Liverpool FC | 5 | 1 | |
| Mo Salah | Liverpool FC | 5 | 2 | |
 | Gianluca Scamacca | Atalanta Bergame | 5 | 0 | |
| Patrik Schick | Bayer Leverkusen | 5 | 0 | |
| 14 |  | Veljko Birmančević | AC Sparta Praha | 4 | 0 |
 | Mojmír Chytil | Slavia Prague | 4 | 0 | |
 | Thijs Dallinga | Toulouse FC | 4 | 1 | |
 | Ángel Di María | SL Benfica | 4 | 3 | |
 | Kristian Eriksen | Molde FK | 4 | 0 | |
| Cody Gakpo | Liverpool FC | 4 | 0 | |
| Vincenzo Grifo | SC Fribourg | 4 | 2 | |
 | Ruben Loftus-Cheek | AC Milan | 4 | 0 | |
| Lucas Paquetá | West Ham United | 4 | 0 | |
| Luis Muriel | Atalanta Bergame | 4 | 1 | |
| Roland Sallai | SC Fribourg | 4 | 0 | |
| 25 |  | Chuba Akpom | AFC Ajax | 3 | 0 |
| Shavy Warren Babicka | Toulouse FC | 3 | 0 | |
| Andrea Belotti | AS Rome | 3 | 0 | |
 | Ludovic Blas | Stade Rennais | 3 | 1 | |
| Benjamin Bourigeaud | Stade Rennais | 3 | 2 | |
| Luis Díaz | Liverpool FC | 3 | 0 | |
| Diogo Jota | Liverpool FC | 3 | 0 | |
| David Douděra | Slavia Prague | 3 | 0 | |
 | Ayoub El Kaabi | Olympiacos le Pirée | 3 | 0 | |
| Jeremie Frimpong | Bayer Leverkusen | 3 | 0 | |
| Gonçalo Inácio | Sporting CP | 3 | 0 | |
| Lukáš Haraslín | AC Sparta Praha | 3 | 0 | |
| Jan Kuchta | AC Sparta Praha | 3 | 0 | |
| Gianluca Mancini | AS Rome | 3 | 0 | |
| Chancel Mbemba | Olympique de Marseille | 3 | 0 | |
| Pedro Gonçalves | Sporting CP | 3 | 2 | |
| Daniel Podence | Olympiacos le Pirée | 3 | 0 | |
| Rafael Leão | AC Milan | 3 | 0 | |
| Ivan Schranz | Slavia Prague | 3 | 0 | |
 | Abdallah Sima | Glasgow Rangers | 3 | 0 | |
 | Alexander Sørloth | Villarreal CF | 3 | 0 | |
| Jordan Veretout | Olympique de Marseille | 3 | 1 | |
| Florian Wirtz | Bayer Leverkusen | 3 | 0 | |
| Abdellah Zoubir | Qarabağ FK | 3 | 0 | |
| 49 | | Álex Baena | Villarreal CF | 2 | 0 |
| Álex Grimaldo | Bayer Leverkusen | 2 | 0 | |
 | Mohamed Amoura | Union Saint-Gilloise | 2 | 0 | |
| Ansu Fati | Brighton & Hove Albion | 2 | 0 | |
 | Ayoze Pérez | Betis Séville | 2 | 0 | |
 | Simon Banza | Sporting Braga | 2 | 1 | |
 | Chris Bedia | Servette FC | 2 | 1 | |
| Yassine Benzia | Qarabağ FK | 2 | 0 | |
 | William Bøving | Sturm Graz | 2 | 0 | |
| Emil Breivik | Molde FK | 2 | 0 | |
| Brian Brobbey | AFC Ajax | 2 | 0 | |
| Jonathan Clauss | Olympique de Marseille | 2 | 0 | |
| Sebastián Coates | Sporting CP | 2 | 0 | |
| Charles De Ketelaere | Atalanta Bergame | 2 | 0 | |
| Ritsu Dōan | SC Fribourg | 2 | 0 | |
| Paulo Dybala | AS Rome | 2 | 0 | |
 | Ifet Đakovac | TSC Bačka Topola | 2 | 0 | |
| Magnus Eikrem | Molde FK | 2 | 0 | |
| Amine Gouiri | Stade Rennais | 2 | 0 | |
| Ryan Gravenberch | Liverpool FC | 2 | 0 | |
| Fredrik Gulbrandsen | Molde FK | 2 | 0 | |
| Adam Hložek | Bayer Leverkusen | 2 | 0 | |
| Jonas Hofmann | Bayer Leverkusen | 2 | 0 | |
| Václav Jurečka | Slavia Prague | 2 | 0 | |
 | Aleksandr Kokorin | Aris Limassol | 2 | 1 | |
| Ladislav Krejčí | AC Sparta Praha | 2 | 0 | |
| Leandro Andrade | Qarabağ FK | 2 | 0 | |
| Lukáš Masopust | Slavia Prague | 2 | 0 | |
| Igoh Ogbu | Slavia Prague | 2 | 0 | |
| Lorenzo Pellegrini | AS Rome | 2 | 0 | |
| Ángelo Preciado | AC Sparta Praha | 2 | 0 | |
| Cameron Puertas | Union Saint-Gilloise | 2 | 1 | |
| Christian Pulišić | AC Milan | 2 | 0 | |
| Rafa Silva | SL Benfica | 2 | 0 | |
| Fabian Rieder | Stade Rennais | 2 | 0 | |
| Ismaïla Sarr | Olympique de Marseille | 2 | 0 | |
| Tomáš Souček | West Ham United | 2 | 0 | |
| Gabriel Suazo | Toulouse FC | 2 | 0 | |
| Dominik Szoboszlai | Liverpool FC | 2 | 0 | |
| Edmond Tapsoba | Bayer Leverkusen | 2 | 0 | |
| Kenneth Taylor | AFC Ajax | 2 | 0 | |
 | Cristian Tovar | FC Sheriff | 2 | 0 | |
| 91 | | Junior Adamu | SC Fribourg | 1 | 0 |
| Simon Adingra | Brighton & Hove Albion | 1 | 0 | |
| Amine Adli | Bayer Leverkusen | 1 | 0 | |
| Nayef Aguerd | West Ham United | 1 | 0 | |
| Aitor Ruibal | Betis Séville | 1 | 0 | |
| Edson Álvarez | West Ham United | 1 | 0 | |
| Álvaro Djaló | Sporting Braga | 1 | 0 | |
| David Ankeye | FC Sheriff | 1 | 0 | |
| Michail Antonio | West Ham United | 1 | 0 | |
| Lorenz Assignon | Stade Rennais | 1 | 0 | |
| Nəriman Axundzadə | Qarabağ FK | 1 | 0 | |
 | Abdülkerim Bardakçı | Galatasaray | 1 | 0 | |
| Toral Bayramov | Qarabağ FK | 1 | 1 | |
| Leo Bengtsson | Aris Limassol | 1 | 0 | |
| Steven Berghuis | AFC Ajax | 1 | 0 | |
| Steven Bergwijn | AFC Ajax | 1 | 1 | |
| Martin Bjørnbak | Molde FK | 1 | 0 | |
| Giovanni Bonfanti | Atalanta Bergame | 1 | 0 | |
| Borja Iglesias | Bayer Leverkusen | 1 | 0 | |
| Edoardo Bove | AS Rome | 1 | 0 | |
| Jarrod Bowen | West Ham United | 1 | 0 | |
| Christian Burgess | Union Saint-Gilloise | 1 | 0 | |
| Todd Cantwell | Glasgow Rangers | 1 | 0 | |
| Étienne Capoue | Villarreal CF | 1 | 0 | |
| Carlos Forbs | AFC Ajax | 1 | 0 | |
 | Tjaronn Chery | Maccabi Haifa | 1 | 0 | |
| Aleksandar Ćirković | TSC Bačka Topola | 1 | 0 | |
| Bobby Clark | Liverpool FC | 1 | 0 | |
| Aaron Cresswell | West Ham United | 1 | 0 | |
| Bryan Cristante | AS Rome | 1 | 0 | |
| Enzo Crivelli | Servette FC | 1 | 0 | |
| Dani Parejo | Villarreal CF | 1 | 0 | |
| Danilo | Glasgow Rangers | 1 | 0 | |
| Dean David | Maccabi Haifa | 1 | 0 | |
 | David Costa | RC Lens | 1 | 0 | |
| Kerem Demirbay | Galatasaray | 1 | 0 | |
| Mikkel Desler | Toulouse FC | 1 | 0 | |
| Cyriel Dessers | Glasgow Rangers | 1 | 0 | |
| Assane Diao | Betis Séville | 1 | 0 | |
| Berat Djimsiti | Atalanta Bergame | 1 | 0 | |
| Aron Dønnum | Toulouse FC | 1 | 0 | |
| Éderson | Atalanta Bergame | 1 | 0 | |
| Marcus Edwards | Sporting CP | 1 | 0 | |
| Maximilian Eggestein | SC Fribourg | 1 | 0 | |
 | Eguinaldo | Chakhtior Donetsk | 1 | 0 | |
| Youssef El-Arabi | Olympiacos le Pirée | 1 | 0 | |
| Wataru Endo | Liverpool FC | 1 | 0 | |
| Abde Ezzalzouli | Betis Séville | 1 | 0 | |
 | Florian Flecker | LASK | 1 | 0 | |
| Kostas Fortounis | Olympiacos le Pirée | 1 | 0 | |
| Matteo Gabbia | AC Milan | 1 | 0 | |
 | Mijat Gaćinović | AEK Athènes | 1 | 0 | |
 | Silvère Ganvoula | BSC Young Boys | 1 | 1 | |
| Levi García | AEK Athènes | 1 | 0 | |
| Gerard Moreno | Villarreal CF | 1 | 1 | |
 | Santiago Giménez | Feyenoord | 1 | 0 | |
| Olivier Giroud | AC Milan | 1 | 0 | |
| Pascal Groß | Brighton & Hove Albion | 1 | 0 | |
| Amine Harit | Olympique de Marseille | 1 | 1 | |
| Sascha Horvath | LASK | 1 | 1 | |
 | Srđan Hrstić | BK Häcken | 1 | 0 | |
| Mauro Icardi | Galatasaray | 1 | 0 | |
| Igor Paixão | Feyenoord | 1 | 0 | |
| Ilias Akhomach | Villarreal CF | 1 | 0 | |
| Isco | Betis Séville | 1 | 0 | |
| Marko Janković | Qarabağ FK | 1 | 1 | |
| João Moutinho | Sporting Braga | 1 | 1 | |
| José Morales | Villarreal CF | 1 | 0 | |
| Luka Jović | AC Milan | 1 | 0 | |
| Juan Miranda | Betis Séville | 1 | 0 | |
| Matěj Jurásek | Slavia Prague | 1 | 0 | |
| Arnaud Kalimuendo | Stade Rennais | 1 | 0 | |
| Eric Kitolano | Molde FK | 1 | 0 | |
| Geoffrey Kondogbia | Olympique de Marseille | 1 | 0 | |
| Tom Lawrence | Glasgow Rangers | 1 | 0 | |
| Marin Ljubičić | LASK | 1 | 0 | |
| Ademola Lookman | Atalanta Bergame | 1 | 0 | |
| Alexis Mac Allister | Liverpool FC | 1 | 1 | |
| Frank Magri | Toulouse FC | 1 | 0 | |
| Marc Roca | Betis Séville | 1 | 0 | |
| Georgios Masouras | Olympiacos le Pirée | 1 | 0 | |
| Matheus Silva | Qarabağ FK | 1 | 0 | |
| Mykola Matvienko | Chakhtior Donetsk | 1 | 0 | |
| Jerome Mbekeli | FC Sheriff | 1 | 0 | |
| Ross McCausland | Glasgow Rangers | 1 | 0 | |
| Dries Mertens | Galatasaray | 1 | 0 | |
| Yerson Mosquera | Villarreal CF | 1 | 0 | |
| Alex Moucketou-Moussounda | Aris Limassol | 1 | 0 | |
| Faris Moumbagna | Olympique de Marseille | 1 | 0 | |
| Bəhlul Mustafazadə | Qarabağ FK | 1 | 0 | |
| Iliman Ndiaye | Olympique de Marseille | 1 | 0 | |
| Sebastián Palacios | Panathinaikos | 1 | 0 | |
| Miloš Pantović | TSC Bačka Topola | 1 | 0 | |
| Mario Pašalić | Atalanta Bergame | 1 | 0 | |
| Paulinho | Sporting CP | 1 | 0 | |
| Nemanja Petrović | TSC Bačka Topola | 1 | 0 | |
| Maximilian Philipp | SC Fribourg | 1 | 0 | |
 | Fabian Piasecki | Raków Częstochowa | 1 | 0 | |
| Orbelín Pineda | AEK Athènes | 1 | 0 | |
| Niccolò Pisilli | AS Rome | 1 | 0 | |
| Ezequiel Ponce | AEK Athènes | 1 | 0 | |
| Alexander Prass | Sturm Graz | 1 | 0 | |
| Jarell Quansah | Liverpool FC | 1 | 0 | |
| Tijjani Reijnders | AC Milan | 1 | 0 | |
| Rodinei | Olympiacos le Pirée | 1 | 0 | |
| Roger Fernandes | Sporting Braga | 1 | 0 | |
| Merlin Röhl | SC Fribourg | 1 | 0 | |
| Kemar Roofe | Glasgow Rangers | 1 | 0 | |
| Steve Rouiller | Servette FC | 1 | 0 | |
| Matteo Ruggeri | Atalanta Bergame | 1 | 0 | |
| Milan Rundić | Raków Częstochowa | 1 | 0 | |
| Ibrahim Salah | Stade Rennais | 1 | 0 | |
| Santi Comesaña | Villarreal CF | 1 | 0 | |
| Giorgio Scalvini | Atalanta Bergame | 1 | 0 | |
| Abdoulaye Seck | Maccabi Haifa | 1 | 0 | |
| Djibril Sidibé | AEK Athènes | 1 | 0 | |
| Kiliann Sildillia | SC Fribourg | 1 | 0 | |
| Momodou Sonko | BK Häcken | 1 | 0 | |
| Andraž Šporar | Panathinaikos | 1 | 0 | |
| Petar Stanić | TSC Bačka Topola | 1 | 0 | |
| Dujon Sterling | Glasgow Rangers | 1 | 0 | |
| Georgiy Sudakov | Chakhtior Donetsk | 1 | 1 | |
| Maksym Taloverov | LASK | 1 | 0 | |
| Nathan Tella | Bayer Leverkusen | 1 | 0 | |
| Martin Terrier | Stade Rennais | 1 | 0 | |
| Muhamed Tijani | Slavia Prague | 1 | 1 | |
| Adrien Truffert | Stade Rennais | 1 | 0 | |
| Indrit Tuci | AC Sparta Praha | 1 | 0 | |
| Filip Ugrinić | BSC Young Boys | 1 | 0 | |
| Moses Usor | LASK | 1 | 0 | |
| Domagoj Vida | AEK Athènes | 1 | 0 | |
| Martin Vitík | AC Sparta Praha | 1 | 0 | |
| Vitinha | Olympique de Marseille | 1 | 0 | |
| Elye Wahi | RC Lens | 1 | 0 | |
| Noah Weißhaupt | SC Fribourg | 1 | 0 | |
| Danny Welbeck | Brighton & Hove Albion | 1 | 0 | |
| Szymon Włodarczyk | Sturm Graz | 1 | 1 | |
| John Yeboah | Raków Częstochowa | 1 | 0 | |
| Bertuğ Yıldırım | Stade Rennais | 1 | 0 | |
| Christos Zafeiris | Slavia Prague | 1 | 0 | |
| Robert Žulj | LASK | 1 | 0 |
