| # | Nom | Équipe | Buts | Pén | |
|---|---|---|---|---|---|
| 1 |  | Lautaro Martínez | Inter Milan | 23 | 2 |
| 2 |  | Dušan Vlahović | Juventus | 16 | 2 |
| 3 |  | Albert Guðmundsson | Genoa CFC | 14 | 4 |
 | Victor Osimhen | SSC Naples | 14 | 3 | |
| 5 | | Hakan Çalhanoğlu | Inter Milan | 13 | 10 |
 | Paulo Dybala | AS Rome | 13 | 7 | |
 | Olivier Giroud | AC Milan | 13 | 4 | |
| 8 | | Marcus Thuram | Inter Milan | 12 | 0 |
 | Duván Zapata | Torino FC | 12 | 0 | |
| 10 |  | Teun Koopmeiners | Atalanta Bergame | 11 | 2 |
| Romelu Lukaku | AS Rome | 11 | 0 | |
 | Matías Soulé | Frosinone Calcio | 11 | 5 | |
 | Joshua Zirkzee | Bologna FC | 11 | 2 | |
| 14 | | Khvicha Kvaratskhelia | SSC Naples | 10 | 0 |
| Riccardo Orsolini | Bologna FC | 10 | 2 | |
 | Andrea Pinamonti | Sassuolo Calcio | 10 | 1 | |
| Christian Pulišić | AC Milan | 10 | 0 | |
| 18 | | Domenico Berardi | Sassuolo Calcio | 9 | 5 |
 | Nicolás González | ACF Fiorentina | 9 | 1 | |
| Ademola Lookman | Atalanta Bergame | 9 | 0 | |
| Gianluca Scamacca | Atalanta Bergame | 9 | 0 | |
| 22 |  | Andrea Colpani | AC Monza | 8 | 0 |
| Milan Đurić | AC Monza | 8 | 1 | |
| Matteo Politano | SSC Naples | 8 | 2 | |
| 25 | | Giacomo Bonaventura | ACF Fiorentina | 7 | 0 |
| Federico Chiesa | Juventus | 7 | 1 | |
| Charles De Ketelaere | Atalanta Bergame | 7 | 1 | |
 | Ciro Immobile | Lazio de Rome | 7 | 4 | |
 | Lorenzo Lucca | Udinese Calcio | 7 | 0 | |
| Cyril Ngonge | SSC Naples | 7 | 0 | |
| Lorenzo Pellegrini | AS Rome | 7 | 0 | |
| Rafael Leão | AC Milan | 7 | 0 | |
| 33 | | Lucas Beltrán | ACF Fiorentina | 6 | 1 |
 | Antonio Candreva | US Salernitana 1919 | 6 | 1 | |
| Walid Cheddira | Frosinone Calcio | 6 | 1 | |
| Éderson | Atalanta Bergame | 6 | 0 | |
| Lewis Ferguson | Bologna FC | 6 | 0 | |
| Luka Jović | AC Milan | 6 | 0 | |
 | Nikola Krstović | US Lecce | 6 | 1 | |
| Ruben Loftus-Cheek | AC Milan | 6 | 0 | |
| Noah Okafor | AC Milan | 6 | 0 | |
| Matteo Pessina | AC Monza | 6 | 4 | |
| Mateo Retegui | Genoa CFC | 6 | 0 | |
| Kristian Thorstvedt | Sassuolo Calcio | 6 | 0 | |
| 45 | | Federico Dimarco | Inter Milan | 5 | 0 |
| Giovanni Fabbian | Bologna FC | 5 | 0 | |
| Felipe Anderson | Lazio de Rome | 5 | 0 | |
| Davide Frattesi | Inter Milan | 5 | 0 | |
 | Gianluca Gaetano | Cagliari Calcio | 5 | 1 | |
| Theo Hernández | AC Milan | 5 | 1 | |
| Armand Laurienté | Sassuolo Calcio | 5 | 0 | |
| Luis Alberto | Lazio de Rome | 5 | 0 | |
| Lucas Martínez Quarta | ACF Fiorentina | 5 | 0 | |
| Luca Mazzitelli | Frosinone Calcio | 5 | 0 | |
| Mario Pašalić | Atalanta Bergame | 5 | 1 | |
| Roberto Piccoli | US Lecce | 5 | 1 | |
| Giacomo Raspadori | SSC Naples | 5 | 0 | |
| Antonio Sanabria | Torino FC | 5 | 2 | |
| Florian Thauvin | Udinese Calcio | 5 | 1 | |
| Matías Vecino | Lazio de Rome | 5 | 0 | |
| Nicolas Viola | Cagliari Calcio | 5 | 0 | |
| Mattia Zaccagni | Lazio de Rome | 5 | 0 | |
| 63 | | Andrea Belotti | ACF Fiorentina | 4 | 0 |
| Marco Brescianini | Frosinone Calcio | 4 | 0 | |
| Taty Castellanos | Lazio de Rome | 4 | 0 | |
| Lorenzo Colombo | AC Monza | 4 | 0 | |
| Dany Mota | AC Monza | 4 | 0 | |
| Boulaye Dia | US Salernitana 1919 | 4 | 1 | |
 | Michael Folorunsho | Hellas Verona | 4 | 0 | |
| Federico Gatti | Juventus | 4 | 0 | |
| Zito Luvumbo | Cagliari Calcio | 4 | 0 | |
| Daniel Maldini | AC Monza | 4 | 0 | |
| Gianluca Mancini | AS Rome | 4 | 0 | |
 | M'Baye Niang | Empoli FC | 4 | 3 | |
| Leonardo Pavoletti | Cagliari Calcio | 4 | 0 | |
| Roberto Pereyra | Udinese Calcio | 4 | 1 | |
| Adrien Rabiot | Juventus | 4 | 0 | |
| Alexis Saelemaekers | Bologna FC | 4 | 0 | |
| Lazar Samardžić | Udinese Calcio | 4 | 0 | |
| Fikayo Tomori | AC Milan | 4 | 0 | |
| Szymon Żurkowski | Empoli FC | 4 | 0 | |
| 82 | | Francesco Acerbi | Inter Milan | 3 | 0 |
| Houssem Aouar | AS Rome | 3 | 0 | |
| Sardar Azmoun | AS Rome | 3 | 0 | |
| Federico Bonazzoli | Hellas Verona | 3 | 0 | |
| Alessandro Buongiorno | Torino FC | 3 | 0 | |
| Matteo Cancellieri | Empoli FC | 3 | 0 | |
| Francesco Caputo | Empoli FC | 3 | 1 | |
| Bryan Cristante | AS Rome | 3 | 0 | |
| Denzel Dumfries | Inter Milan | 3 | 0 | |
| Caleb Ekuban | Genoa CFC | 3 | 0 | |
| Stephan El Shaarawy | AS Rome | 3 | 0 | |
| Abdou Harroui | Frosinone Calcio | 3 | 1 | |
| Thomas Henry | Hellas Verona | 3 | 0 | |
| Jonathan Ikoné | ACF Fiorentina | 3 | 0 | |
| Gustav Isaksen | Lazio de Rome | 3 | 0 | |
| Kaio Jorge | Frosinone Calcio | 3 | 1 | |
| Grigoris Kastanos | US Salernitana 1919 | 3 | 0 | |
| Giulio Maggiore | US Salernitana 1919 | 3 | 0 | |
| Ruslan Malinovskiy | Genoa CFC | 3 | 0 | |
| Rolando Mandragora | ACF Fiorentina | 3 | 0 | |
| Arkadiusz Milik | Juventus | 3 | 0 | |
| Aleksey Miranchuk | Atalanta Bergame | 3 | 0 | |
| Tijjani Noslin | Hellas Verona | 3 | 0 | |
| Rémi Oudin | US Lecce | 3 | 0 | |
| Leandro Paredes | AS Rome | 3 | 3 | |
| Nemanja Radonjić | Torino FC | 3 | 0 | |
| Eldor Shomurodov | Cagliari Calcio | 3 | 0 | |
| Loum Tchaouna | US Salernitana 1919 | 3 | 0 | |
| Nikola Vlašić | Torino FC | 3 | 0 | |
| Piotr Zieliński | SSC Naples | 3 | 1 | |
| 112 | | Pontus Almqvist | US Lecce | 2 | 0 |
| Marko Arnautović | Inter Milan | 2 | 0 | |
| Nedim Bajrami | Sassuolo Calcio | 2 | 0 | |
| Tommaso Baldanzi | AS Rome | 2 | 0 | |
| Lameck Banda | US Lecce | 2 | 0 | |
| Mattia Bani | Genoa CFC | 2 | 0 | |
| Antonín Barák | ACF Fiorentina | 2 | 0 | |
| Nicolò Barella | Inter Milan | 2 | 0 | |
| Yann Bisseck | Inter Milan | 2 | 0 | |
| Bremer | Juventus | 2 | 0 | |
| Andrea Cambiaso | Juventus | 2 | 0 | |
| Valentin Carboni | AC Monza | 2 | 0 | |
| Diego Coppola | Hellas Verona | 2 | 0 | |
| Matteo Darmian | Inter Milan | 2 | 0 | |
| Lorenzo De Silvestri | Bologna FC | 2 | 0 | |
| Patrick Dorgu | US Lecce | 2 | 0 | |
| Alberto Dossena | Cagliari Calcio | 2 | 0 | |
| Radu Drăgușin | Genoa CFC | 2 | 0 | |
| Alfred Duncan | ACF Fiorentina | 2 | 0 | |
| Oussama El Azzouzi | Bologna FC | 2 | 0 | |
| Eljif Elmas | SSC Naples | 2 | 0 | |
| Morten Frendrup | Genoa CFC | 2 | 0 | |
| Valentin Gendrey | US Lecce | 2 | 0 | |
| Mattéo Guendouzi | Lazio de Rome | 2 | 0 | |
| Dean Huijsen | AS Rome | 2 | 0 | |
| Ivan Ilić | Torino FC | 2 | 0 | |
| Christian Kouamé | ACF Fiorentina | 2 | 0 | |
| Gianluca Lapadula | Cagliari Calcio | 2 | 0 | |
| Darko Lazović | Hellas Verona | 2 | 0 | |
| Pol Lirola | Frosinone Calcio | 2 | 0 | |
| Charalampos Lykogiannis | Bologna FC | 2 | 0 | |
| Matheus Henrique | Sassuolo Calcio | 2 | 0 | |
| Henrikh Mkhitaryan | Inter Milan | 2 | 0 | |
| Ilario Monterisi | Frosinone Calcio | 2 | 0 | |
| Luis Muriel | Atalanta Bergame | 2 | 0 | |
| M'Bala Nzola | ACF Fiorentina | 2 | 1 | |
| Jens Odgaard | Bologna FC | 2 | 0 | |
| Gaetano Oristanio | Cagliari Calcio | 2 | 0 | |
| Martín Payero | Udinese Calcio | 2 | 0 | |
| Luca Ranieri | ACF Fiorentina | 2 | 0 | |
| Tijjani Reijnders | AC Milan | 2 | 0 | |
| Reinier | Frosinone Calcio | 2 | 0 | |
| Amir Rrahmani | SSC Naples | 2 | 0 | |
| Daniele Rugani | Juventus | 2 | 0 | |
| Alexis Sánchez | Inter Milan | 2 | 1 | |
| Nicola Sansone | US Lecce | 2 | 0 | |
| Riccardo Sottil | ACF Fiorentina | 2 | 0 | |
| Ibrahim Sulemana | Cagliari Calcio | 2 | 0 | |
| Morten Thorsby | Genoa CFC | 2 | 0 | |
| El Bilal Touré | Atalanta Bergame | 2 | 0 | |
| Walace | Udinese Calcio | 2 | 0 | |
| Davide Zappacosta | Atalanta Bergame | 2 | 0 | |
| Zarraga | Udinese Calcio | 2 | 0 | |
| Nadir Zortea | Frosinone Calcio | 2 | 0 | |
| 166 | | Tammy Abraham | AS Rome | 1 | 0 |
| Yacine Adli | AC Milan | 1 | 0 | |
| Kristjan Asllani | Inter Milan | 1 | 0 | |
| Tommaso Augello | Cagliari Calcio | 1 | 0 | |
| Jaime Báez | Frosinone Calcio | 1 | 0 | |
| Mitchel Bakker | Atalanta Bergame | 1 | 0 | |
| Alessandro Bastoni | Inter Milan | 1 | 0 | |
| Simone Bastoni | Empoli FC | 1 | 0 | |
| Raoul Bellanova | Torino FC | 1 | 0 | |
| Sam Beukema | Bologna FC | 1 | 0 | |
| Cristiano Biraghi | ACF Fiorentina | 1 | 0 | |
| Davide Biraschi | Genoa CFC | 1 | 0 | |
| Daniel Boloca | Sassuolo Calcio | 1 | 0 | |
| Warren Bondo | AC Monza | 1 | 0 | |
| Josip Brekalo | ACF Fiorentina | 1 | 0 | |
| Luca Caldirola | AC Monza | 1 | 0 | |
| Nicolò Cambiaghi | Empoli FC | 1 | 0 | |
| Andrea Carboni | AC Monza | 1 | 0 | |
| Danilo Cataldi | Lazio de Rome | 1 | 0 | |
| Alberto Cerri | Empoli FC | 1 | 0 | |
| Samuel Chukwueze | AC Milan | 1 | 0 | |
| Marvin Cuni | Frosinone Calcio | 1 | 0 | |
| Danilo | Juventus | 1 | 0 | |
| Stefan de Vrij | Inter Milan | 1 | 0 | |
| Grégoire Defrel | Sassuolo Calcio | 1 | 0 | |
| Federico Di Francesco | US Lecce | 1 | 0 | |
| Giovanni Di Lorenzo | SSC Naples | 1 | 0 | |
| Ondrej Duda | Hellas Verona | 1 | 0 | |
| Martin Erlić | Sassuolo Calcio | 1 | 0 | |
| Federico Fazio | US Salernitana 1919 | 1 | 0 | |
| Jacopo Fazzini | Empoli FC | 1 | 0 | |
| Gian Marco Ferrari | Sassuolo Calcio | 1 | 0 | |
| Remo Freuler | Bologna FC | 1 | 0 | |
| Matteo Gabbia | AC Milan | 1 | 0 | |
| Gabriel Strefezza | US Lecce | 1 | 1 | |
| Roberto Gagliardini | AC Monza | 1 | 0 | |
| Lautaro Gianetti | Udinese Calcio | 1 | 0 | |
| Emmanuel Gyasi | Empoli FC | 1 | 0 | |
| Emil Holm | Atalanta Bergame | 1 | 0 | |
| Arijon Ibrahimović | Frosinone Calcio | 1 | 0 | |
| Chukwubuikem Ikwuemesi | US Salernitana 1919 | 1 | 0 | |
| Samuel Iling | Juventus | 1 | 0 | |
| Jakub Jankto | Cagliari Calcio | 1 | 0 | |
| Joan Gonzàlez | US Lecce | 1 | 0 | |
| Jovane Cabral | US Salernitana 1919 | 1 | 0 | |
| Juan Jesus | SSC Naples | 1 | 0 | |
| Christian Kabasele | Udinese Calcio | 1 | 0 | |
| Daichi Kamada | Lazio de Rome | 1 | 0 | |
| Hassane Kamara | Udinese Calcio | 1 | 0 | |
| Michael Kayode | ACF Fiorentina | 1 | 0 | |
| Sead Kolašinac | Atalanta Bergame | 1 | 0 | |
| Viktor Kovalenko | Empoli FC | 1 | 0 | |
| Rasmus Kristensen | AS Rome | 1 | 0 | |
| Llorente | AS Rome | 1 | 0 | |
| Manuel Locatelli | Juventus | 1 | 0 | |
| Sandi Lovrič | Udinese Calcio | 1 | 0 | |
| Sebastiano Luperto | Empoli FC | 1 | 0 | |
| Antoine Makoumbou | Cagliari Calcio | 1 | 0 | |
| Mirko Marić | AC Monza | 1 | 0 | |
| Agustin Martegani | US Salernitana 1919 | 1 | 0 | |
| Adam Marušić | Lazio de Rome | 1 | 0 | |
| Junior Messias | Genoa CFC | 1 | 0 | |
| Yerry Mina | Cagliari Calcio | 1 | 1 | |
| Fabio Miretti | Juventus | 1 | 0 | |
| Nikola Moro | Bologna FC | 1 | 0 | |
| Nahitan Nández | Cagliari Calcio | 1 | 1 | |
| Simy Nwankwo | US Salernitana 1919 | 1 | 0 | |
| Mathías Olivera | SSC Naples | 1 | 0 | |
| Leo Østigård | SSC Naples | 1 | 0 | |
| Patric | Lazio de Rome | 1 | 0 | |
| Pedro | Lazio de Rome | 1 | 0 | |
| Luca Pellegrini | Lazio de Rome | 1 | 0 | |
| Andrea Petagna | Cagliari Calcio | 1 | 0 | |
| Lorenzo Pirola | US Salernitana 1919 | 1 | 0 | |
| Uroš Račić | Sassuolo Calcio | 1 | 0 | |
| Hamza Rafia | US Lecce | 1 | 0 | |
| Ylber Ramadani | US Lecce | 1 | 0 | |
| Renato Sanches | AS Rome | 1 | 0 | |
| Samuele Ricci | Torino FC | 1 | 0 | |
| Simone Romagnoli | Frosinone Calcio | 1 | 0 | |
| Perr Schuurs | Torino FC | 1 | 0 | |
| Giovanni Simeone | SSC Naples | 1 | 0 | |
| Jan-Carlo Simić | AC Milan | 1 | 0 | |
| Leonardo Spinazzola | AS Rome | 1 | 0 | |
| Tomáš Suslov | Hellas Verona | 1 | 1 | |
| Karol Świderski | Hellas Verona | 1 | 0 | |
| Chaka Traorè | AC Milan | 1 | 0 | |
| Johan Vásquez | Genoa CFC | 1 | 0 | |
| Samuele Vignato | AC Monza | 1 | 0 | |
| Vitinha | Genoa CFC | 1 | 0 | |
| Cristian Volpato | Sassuolo Calcio | 1 | 0 | |
| Shon Weissman | US Salernitana 1919 | 1 | 0 | |
| Kenan Yıldız | Juventus | 1 | 0 | |
| Gabriele Zappa | Cagliari Calcio | 1 | 0 | |
| Jordan Zemura | Udinese Calcio | 1 | 0 |
