| # | Équipe | Équipe | J | G | N | P | Buts | Diff | PTS | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | FC Barcelone | FC Barcelone | 37 | 27 | 4 | 6 | 99:39 | 60 | 85 |
| 2 |  | Real Madrid | Real Madrid | 37 | 25 | 6 | 6 | 76:38 | 38 | 81 |
| 3 |  | Atlético de Madrid | Atlético | 37 | 21 | 10 | 6 | 64:30 | 34 | 73 |
| 4 |  | Athletic Club | Athletic | 37 | 19 | 13 | 5 | 54:26 | 28 | 70 |
| 5 |  | Villarreal CF | Villarreal | 37 | 19 | 10 | 8 | 67:49 | 18 | 67 |
| 6 |  | Betis Séville | Betis | 37 | 16 | 11 | 10 | 56:49 | 7 | 59 |
| 7 |  | RC Celta | RC Celta | 37 | 15 | 7 | 15 | 57:56 | 1 | 52 |
| 8 |  | Rayo Vallecano | Rayo | 37 | 13 | 12 | 12 | 41:45 | -4 | 51 |
| 9 |  | CA Osasuna | Osasuna | 37 | 12 | 15 | 10 | 47:51 | -4 | 51 |
| 10 |  | RCD Mallorca | Mallorca | 37 | 13 | 8 | 16 | 35:44 | -9 | 47 |
| 11 |  | Real Sociedad | Real Sociedad | 37 | 13 | 7 | 17 | 35:44 | -9 | 46 |
| 12 |  | Valence CF | Valence | 37 | 11 | 12 | 14 | 43:53 | -10 | 45 |
| 13 |  | Getafe CF | Getafe | 37 | 11 | 9 | 17 | 33:37 | -4 | 42 |
| 14 |  | CD Alavés | Alavés | 37 | 10 | 11 | 16 | 37:47 | -10 | 41 |
| 15 |  | Girona FC | Girona | 37 | 11 | 8 | 18 | 44:56 | -12 | 41 |
| 16 |  | Séville FC | Séville FC | 37 | 10 | 11 | 16 | 40:51 | -11 | 41 |
| 17 |  | Espanyol Barcelona | Espanyol | 37 | 10 | 9 | 18 | 38:51 | -13 | 39 |
| 18 |  | CD Leganés | Leganés | 37 | 8 | 13 | 16 | 36:56 | -20 | 37 |
| 19 |  | UD Las Palmas | UD Las Palmas | 37 | 8 | 8 | 21 | 40:59 | -19 | 32 |
| 20 |  | Real Valladolid | Valladolid | 37 | 4 | 4 | 29 | 26:87 | -61 | 16 |
| # | Nom | Équipe | Buts | Pén | |
|---|---|---|---|---|---|
| 1 | | Kylian Mbappé | Real Madrid | 29 | 7 |
| 2 | | Robert Lewandowski | FC Barcelone | 25 | 3 |
| 3 | | Ante Budimir | CA Osasuna | 21 | 8 |
| 4 | | Ayoze Pérez | Villarreal CF | 19 | 0 |
| 5 | | Raphinha | FC Barcelone | 18 | 2 |
| 6 | | Julián Alvarez | Atlético de Madrid | 17 | 4 |
| Alexander Sørloth | Atlético de Madrid | 17 | 1 | |
| 8 | | Oihan Sancet | Athletic Club | 15 | 3 |
| 9 | | Kike García | CD Alavés | 13 | 3 |
| 10 | | Thierno Barry | Villarreal CF | 11 | 1 |
| Hugo Duro | Valence CF | 11 | 1 | |
| Javier Puado | Espanyol Barcelona | 11 | 4 | |
| Dodi Lukébakio | Séville FC | 11 | 1 | |
| Cristhian Stuani | Girona FC | 11 | 3 | |
| Vinícius Junior | Real Madrid | 11 | 2 |
