| # | Nom | Équipe | Buts | Pén | |
|---|---|---|---|---|---|
| 1 |  | Karim Benzema | Real Madrid | 27 | 7 |
| 2 |  | Iago Aspas | RC Celta | 18 | 3 |
| 3 |  | Raúl de Tomás | Espanyol Barcelona | 17 | 5 |
| Vinícius Junior | Real Madrid | 17 | 0 | |
| 5 |  | Juanmi | Betis Séville | 16 | 0 |
 | Enes Ünal | Getafe CF | 16 | 2 | |
| 7 |  | Joselu | CD Alavés | 14 | 6 |
| 8 |  | José Morales | Levante UD | 13 | 3 |
| 9 |  | Ángel Correa | Atlético de Madrid | 12 | 0 |
 | Memphis Depay | FC Barcelone | 12 | 4 | |
| 11 | | Pierre-Emerick Aubameyang | FC Barcelone | 11 | 0 |
 | Carlos Soler | Valence CF | 11 | 7 | |
| Gonçalo Guedes | Valence CF | 11 | 1 | |
| Luis Suárez | Atlético de Madrid | 11 | 2 | |
| 15 | | Borja Iglesias | Betis Séville | 10 | 3 |
 | Arnaut Danjuma | Villarreal CF | 10 | 3 | |
 | Jorge Molina | Granada CF | 10 | 0 | |
| Marco Asensio | Real Madrid | 10 | 0 | |
 | Rafa Mir | Séville FC | 10 | 0 | |
| 20 | | Gerard Moreno | Villarreal CF | 9 | 1 |
 | Mikel Oyarzabal | Real Sociedad | 9 | 4 | |
| 22 |  | Ante Budimir | CA Osasuna | 8 | 2 |
 | Iñaki Williams | Athletic Bilbao | 8 | 1 | |
| João Félix | Atlético de Madrid | 8 | 0 | |
 | Pere Milla | Elche CF | 8 | 0 | |
 | Sergi Guardiola | Rayo Vallecano | 8 | 1 | |
| Luis Suárez | Granada CF | 8 | 0 | |
| Willian José | Betis Séville | 8 | 3 | |
| 29 | | Álvaro García | Rayo Vallecano | 7 | 0 |
 | Álvaro Negredo | Cádiz CF | 7 | 2 | |
| Lucas Boyé | Elche CF | 7 | 0 | |
| Gonzalo Melero | Levante UD | 7 | 2 | |
| Hugo Duro | Getafe CF | 7 | 0 | |
| Choco Lozano | Cádiz CF | 7 | 0 | |
| Roger Martí | Levante UD | 7 | 1 | |
| Santi Mina | RC Celta | 7 | 0 | |
| 37 | | Chimy Ávila | CA Osasuna | 6 | 1 |
| Borja Mayoral | Getafe CF | 6 | 1 | |
| Yannick Carrasco | Atlético de Madrid | 6 | 2 | |
| Luuk de Jong | FC Barcelone | 6 | 0 | |
| Radamel Falcao | Rayo Vallecano | 6 | 0 | |
| Nabil Fekir | Betis Séville | 6 | 0 | |
| Alexander Isak | Real Sociedad | 6 | 2 | |
| Matheus Cunha | Atlético de Madrid | 6 | 0 | |
| Lucas Ocampos | Séville FC | 6 | 0 | |
| Oihan Sancet | Athletic Bilbao | 6 | 0 | |
| Puertas | Granada CF | 6 | 0 | |
| Raúl García | Athletic Bilbao | 6 | 0 | |
| Trigueros | Villarreal CF | 6 | 0 | |
| Yéremy | Villarreal CF | 6 | 0 | |
| 51 | | Álex Moreno | Betis Séville | 5 | 0 |
| Boulaye Dia | Villarreal CF | 5 | 0 | |
| Youssef En-Nesyri | Séville FC | 5 | 1 | |
| Gonzalo Escalante | CD Alavés | 5 | 0 | |
| Fidel | Elche CF | 5 | 1 | |
| Maximiliano Gómez | Valence CF | 5 | 0 | |
| Papu Gómez | Séville FC | 5 | 0 | |
| Kike García | CA Osasuna | 5 | 1 | |
| Érik Lamela | Séville FC | 5 | 0 | |
| Lucas Pérez | Cádiz CF | 5 | 0 | |
 | Vedat Muriqi | RCD Mallorca | 5 | 2 | |
| Pau Torres | Villarreal CF | 5 | 0 | |
| Salva Sevilla | RCD Mallorca | 5 | 4 | |
| Sergio Canales | Betis Séville | 5 | 0 | |
| 65 | | Ansu Fati | FC Barcelone | 4 | 0 |
| Ronald Araújo | FC Barcelone | 4 | 0 | |
| Aritz Elustondo | Real Sociedad | 4 | 0 | |
| Brais Méndez | RC Celta | 4 | 0 | |
| Dani Gómez | Levante UD | 4 | 0 | |
| Dani Rodríguez | RCD Mallorca | 4 | 0 | |
| David García | CA Osasuna | 4 | 0 | |
| Denis Suárez | RC Celta | 4 | 0 | |
| Ferran Torres | FC Barcelone | 4 | 1 | |
| Javier Puado | Espanyol Barcelona | 4 | 0 | |
| Jorge De Frutos | Levante UD | 4 | 0 | |
| Thomas Lemar | Atlético de Madrid | 4 | 0 | |
| Darwin Machís | Granada CF | 4 | 0 | |
| Muniain | Athletic Bilbao | 4 | 1 | |
| Pedraza | Villarreal CF | 4 | 0 | |
| Ivan Rakitić | Séville FC | 4 | 1 | |
| Rodrygo | Real Madrid | 4 | 0 | |
| Rubén Sobrino | Cádiz CF | 4 | 0 | |
| Alexander Sørloth | Real Sociedad | 4 | 0 | |
| 84 | | Abdón | RCD Mallorca | 3 | 0 |
| Alberto Moreno | Villarreal CF | 3 | 0 | |
| Álex | Cádiz CF | 3 | 1 | |
| Álex Berenguer | Athletic Bilbao | 3 | 0 | |
| Enis Bardhi | Levante UD | 3 | 2 | |
| Franco Cervi | RC Celta | 3 | 0 | |
| Samuel Chukwueze | Villarreal CF | 3 | 0 | |
| Frenkie de Jong | FC Barcelone | 3 | 0 | |
| Rodrigo De Paul | Atlético de Madrid | 3 | 0 | |
| Diego Carlos | Séville FC | 3 | 0 | |
| Antoine Griezmann | Atlético de Madrid | 3 | 0 | |
| Iñigo Martínez | Athletic Bilbao | 3 | 0 | |
| Adnan Januzaj | Real Sociedad | 3 | 2 | |
| Laguardia | CD Alavés | 3 | 0 | |
| Lucas Vázquez | Real Madrid | 3 | 0 | |
| Luis Milla | Granada CF | 3 | 3 | |
| Mikel Merino | Real Sociedad | 3 | 0 | |
| Nacho | Real Madrid | 3 | 0 | |
| Randy Nteka | Rayo Vallecano | 3 | 0 | |
| Pedri | FC Barcelone | 3 | 0 | |
| Sandro | Getafe CF | 3 | 0 | |
| Sergi Darder | Espanyol Barcelona | 3 | 0 | |
| Soldado | Levante UD | 3 | 0 | |
| Tete Morente | Elche CF | 3 | 0 | |
| Óscar Trejo | Rayo Vallecano | 3 | 3 | |
| 109 | | David Alaba | Real Madrid | 2 | 0 |
| Alcaraz | Cádiz CF | 2 | 0 | |
| Omar Alderete | Valence CF | 2 | 0 | |
| Aleix Vidal | Espanyol Barcelona | 2 | 0 | |
| Álex Collado | Granada CF | 2 | 0 | |
| Ángel | RCD Mallorca | 2 | 0 | |
| Iddrisu Baba | RCD Mallorca | 2 | 0 | |
| Darío Benedetto | Elche CF | 2 | 0 | |
| Martin Braithwaite | FC Barcelone | 2 | 0 | |
| Busquets | FC Barcelone | 2 | 0 | |
| Leandro Cabrera | Espanyol Barcelona | 2 | 0 | |
| Eduardo Camavinga | Real Madrid | 2 | 0 | |
| Guido Carrillo | Elche CF | 2 | 0 | |
| Catena | Rayo Vallecano | 2 | 0 | |
| Pathé Ciss | Rayo Vallecano | 2 | 0 | |
| Francis Coquelin | Villarreal CF | 2 | 0 | |
| Jesús Corona | Séville FC | 2 | 0 | |
| Cristian Tello | Betis Séville | 2 | 0 | |
| Dani Parejo | Villarreal CF | 2 | 1 | |
| David Silva | Real Sociedad | 2 | 0 | |
| Thomas Delaney | Séville FC | 2 | 0 | |
| Óscar Duarte | Levante UD | 2 | 0 | |
| Alfonso Espino | Cádiz CF | 2 | 0 | |
| Felipe Monteiro | Atlético de Madrid | 2 | 0 | |
| Fer Niño | RCD Mallorca | 2 | 0 | |
| Gabriel Paulista | Valence CF | 2 | 0 | |
| Gavi | FC Barcelone | 2 | 0 | |
| Gayà | Valence CF | 2 | 0 | |
| Germán | Granada CF | 2 | 0 | |
| Isi Palazón | Rayo Vallecano | 2 | 0 | |
| Iván Alejo | Cádiz CF | 2 | 0 | |
| Jordi Alba | FC Barcelone | 2 | 0 | |
| Josan | Elche CF | 2 | 0 | |
| José Campaña | Levante UD | 2 | 0 | |
| Julen Lobete | Real Sociedad | 2 | 0 | |
| Kike Barja | CA Osasuna | 2 | 0 | |
| Kike Pérez | Elche CF | 2 | 0 | |
| Jules Koundé | Séville FC | 2 | 0 | |
| Mamadou Loum | CD Alavés | 2 | 0 | |
| Manu Morlanes | Espanyol Barcelona | 2 | 0 | |
| Mario Hermoso | Atlético de Madrid | 2 | 0 | |
| Martín Zubimendi | Real Sociedad | 2 | 0 | |
| Ferland Mendy | Real Madrid | 2 | 0 | |
| Luka Modrić | Real Madrid | 2 | 1 | |
| Moi Gómez | Villarreal CF | 2 | 0 | |
| Johan Mojica | Elche CF | 2 | 0 | |
| Moncayola | CA Osasuna | 2 | 0 | |
| Munir | Séville FC | 2 | 0 | |
| Nico González | FC Barcelone | 2 | 0 | |
| Nico Melamed | Espanyol Barcelona | 2 | 0 | |
| Nolito | RC Celta | 2 | 0 | |
| Óliver Torres | Séville FC | 2 | 0 | |
| Philippe Coutinho | FC Barcelone | 2 | 1 | |
| Raíllo | RCD Mallorca | 2 | 0 | |
| Renan Lodi | Atlético de Madrid | 2 | 0 | |
| Roberto Torres | CA Osasuna | 2 | 2 | |
| Salvi | Cádiz CF | 2 | 0 | |
| Sergi Roberto | FC Barcelone | 2 | 0 | |
| Sergio Escudero | Granada CF | 2 | 0 | |
| Thiago Galhardo | RC Celta | 2 | 0 | |
| Vesga | Athletic Bilbao | 2 | 0 | |
| Villalibre | Athletic Bilbao | 2 | 0 | |
| Vivian | Athletic Bilbao | 2 | 0 | |
| William Carvalho | Betis Séville | 2 | 0 | |
| 173 | | Marcos Acuña | Séville FC | 1 | 0 |
| Adrià Pedrosa | Espanyol Barcelona | 1 | 0 | |
| Sergio Agüero | FC Barcelone | 1 | 0 | |
| Ander Barrenetxea | Real Sociedad | 1 | 0 | |
| Antonio Sánchez | RCD Mallorca | 1 | 0 | |
| Santiago Arias | Atlético de Madrid | 1 | 0 | |
| Santiago Arzamendia | Cádiz CF | 1 | 0 | |
| Gareth Bale | Real Madrid | 1 | 0 | |
| Balliu | Rayo Vallecano | 1 | 0 | |
| Keidi Bare | Espanyol Barcelona | 1 | 0 | |
| Bebé | Rayo Vallecano | 1 | 0 | |
| Bigas | Elche CF | 1 | 0 | |
| Darko Brašanac | CA Osasuna | 1 | 0 | |
| Brian Oliván | RCD Mallorca | 1 | 0 | |
| Étienne Capoue | Villarreal CF | 1 | 0 | |
| Carles Aleñá | Getafe CF | 1 | 0 | |
| Casemiro | Real Madrid | 1 | 0 | |
| Coke | Levante UD | 1 | 0 | |
| Cote | CA Osasuna | 1 | 0 | |
| Dani Alves | FC Barcelone | 1 | 0 | |
| Dani Carvajal | Real Madrid | 1 | 0 | |
| Darío Poveda | Getafe CF | 1 | 0 | |
| De Marcos | Athletic Bilbao | 1 | 0 | |
| Ousmane Dembélé | FC Barcelone | 1 | 0 | |
| Domingos Duarte | Granada CF | 1 | 0 | |
| Eder Militão | Real Madrid | 1 | 0 | |
| Édgar González | Betis Séville | 1 | 0 | |
| Édgar Méndez | CD Alavés | 1 | 0 | |
| Abde Ezzalzouli | FC Barcelone | 1 | 0 | |
| Fernando | Séville FC | 1 | 0 | |
| Ferrán Jutglà | FC Barcelone | 1 | 0 | |
| Juan Foyth | Villarreal CF | 1 | 0 | |
| Fran Beltrán | RC Celta | 1 | 0 | |
| Fran García | Rayo Vallecano | 1 | 0 | |
| José Giménez | Atlético de Madrid | 1 | 0 | |
| Giovanni González | RCD Mallorca | 1 | 0 | |
| Clément Grenier | RCD Mallorca | 1 | 0 | |
| Varazdat Haroyan | Cádiz CF | 1 | 0 | |
| Yangel Herrera | Espanyol Barcelona | 1 | 0 | |
| Hugo Guillamón | Valence CF | 1 | 0 | |
| Hugo Mallo | RC Celta | 1 | 0 | |
| Oussama Idrissi | Cádiz CF | 1 | 0 | |
| Iñigo Pérez | CA Osasuna | 1 | 0 | |
| Isco | Real Madrid | 1 | 0 | |
| Jaime Mata | Getafe CF | 1 | 0 | |
| Javi Martínez | CA Osasuna | 1 | 0 | |
| Jon Guridi | Real Sociedad | 1 | 0 | |
| Jorge Cuenca | Getafe CF | 1 | 0 | |
| Jorge Miramón | Levante UD | 1 | 0 | |
| Luka Jović | Real Madrid | 1 | 0 | |
| Kike Hermoso | Betis Séville | 1 | 0 | |
| Koke | Atlético de Madrid | 1 | 0 | |
| Geoffrey Kondogbia | Atlético de Madrid | 1 | 0 | |
| Toni Kroos | Real Madrid | 1 | 0 | |
| Takefusa Kubo | RCD Mallorca | 1 | 0 | |
| Robin Le Normand | Real Sociedad | 1 | 0 | |
| Kang-in Lee | RCD Mallorca | 1 | 0 | |
| Giovani Lo Celso | Villarreal CF | 1 | 0 | |
| Lucas Torró | CA Osasuna | 1 | 0 | |
| Luis Rioja | CD Alavés | 1 | 0 | |
| Nemanja Maksimović | Getafe CF | 1 | 0 | |
| Mickaël Malsa | Levante UD | 1 | 0 | |
| Aïssa Mandi | Villarreal CF | 1 | 0 | |
| Manu Sánchez | CA Osasuna | 1 | 0 | |
| Manu Vallejo | CD Alavés | 1 | 0 | |
| Marc Bartra | Betis Séville | 1 | 0 | |
| Marcos André | Valence CF | 1 | 0 | |
| Mariano | Real Madrid | 1 | 0 | |
| Mario Hernández | Rayo Vallecano | 1 | 0 | |
| Miguel | CD Alavés | 1 | 0 | |
| Montoro | Granada CF | 1 | 0 | |
| Loren Morón | Espanyol Barcelona | 1 | 0 | |
| Yunus Musah | Valence CF | 1 | 0 | |
| Shkodran Mustafi | Levante UD | 1 | 0 | |
| Nico Serrano | Athletic Bilbao | 1 | 0 | |
| Oier | CA Osasuna | 1 | 0 | |
| Lucas Olaza | Elche CF | 1 | 0 | |
| Mathías Olivera | Getafe CF | 1 | 0 | |
| Pablo Maffeo | RCD Mallorca | 1 | 0 | |
| Paco Alcácer | Villarreal CF | 1 | 0 | |
| Pere Pons | CD Alavés | 1 | 0 | |
| Germán Pezzella | Betis Séville | 1 | 0 | |
| Cristiano Piccini | Valence CF | 1 | 0 | |
| Piqué | FC Barcelone | 1 | 0 | |
| Ezequiel Ponce | Elche CF | 1 | 0 | |
| Portu | Real Sociedad | 1 | 1 | |
| Rafinha | Real Sociedad | 1 | 0 | |
| Riqui Puig | FC Barcelone | 1 | 0 | |
| Róber | Levante UD | 1 | 0 | |
| Enzo Roco | Elche CF | 1 | 0 | |
| Rodri | Betis Séville | 1 | 0 | |
| Guido Rodríguez | Betis Séville | 1 | 0 | |
| Rubén García | CA Osasuna | 1 | 0 | |
| Rubén Rochina | Granada CF | 1 | 0 | |
| Franco Russo | RCD Mallorca | 1 | 0 | |
| Santi Comesaña | Rayo Vallecano | 1 | 0 | |
| Sergi Gómez | Espanyol Barcelona | 1 | 0 | |
| Son | Levante UD | 1 | 0 | |
| Myrto Uzuni | Granada CF | 1 | 0 | |
| Víctor Díaz | Granada CF | 1 | 0 | |
| Tonny Vilhena | Espanyol Barcelona | 1 | 0 | |
| Šime Vrsaljko | Atlético de Madrid | 1 | 0 | |
| Daniel Wass | Atlético de Madrid | 1 | 0 | |
| Lei Wu | Espanyol Barcelona | 1 | 0 | |
| Yuri | Athletic Bilbao | 1 | 0 | |
| Zarraga | Athletic Bilbao | 1 | 1 |
